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Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Both mouse and rat models are effective for testing alopecia areata treatments.

Keratinocytes control how melanocytes work.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Applying calreticulin can speed up wound healing in diabetics.

People with alopecia areata have higher levels of a heart disease marker than those without hair loss.

PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Freezing gamma-irradiated amniotic fluid may help hair growth and speed up the growth phase.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Dermal factors are crucial in regulating melanin production in skin.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

The reviewers suggest clarifying and expanding on the role of inflammation in stem cell-related cancer development.

The reviewers suggest major revisions for clarity and inclusion of recent findings on inflammation's role in cancer.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.

The revised manuscript on how inflammation affects cancer stem cells was accepted after addressing issues with clarity and detail.

In September 2016, there were major advancements and promising clinical trials in stem cell research and regenerative medicine.

Non-thermal plasma treatment makes mouse skin thicker and increases growth factors without harming the tissue.

Hair cortisol levels peak in the third trimester and decline postpartum.

A new compound from Royoporus badius activates immune cells and induces inflammatory responses.

A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.