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The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.

Hair restoration has evolved from surgery to drugs to potential gene therapy, with improved results and ongoing research driven by high demand.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.

Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Certain foods and supplements can help treat skin diseases alongside medication.

PRP helps with skin, hair, and wound treatments but needs more research for standard use.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

Lifestyle changes like diet and exercise are key for treating overweight women with polycystic ovary syndrome.

Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Bimatoprost is effective for growing longer, thicker, and darker eyelashes.

Baricitinib was effective in treating a patient with dermatomyositis and hair loss.

The control system for hair growth cycles is not well understood and needs more research.

Finasteride improved symptoms in a schizophrenia patient.

Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.

Lower LDL-c levels predict higher COVID-19 mortality.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

A new gene variant causes glucocorticoid resistance in a mother and son.

Dexamethasone increases androgen receptor activity in scalp cells, which might explain stress-related hair loss.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.