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Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Intense exercise at night can delay the body's internal clock gene expression by 2 to 4 hours.

HSD11b1 affects skin nerves and increases non-histaminergic itch.

Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.

PCOS requires personalized treatment to improve life quality and reduce health risks.

PRP helps with skin, hair, and wound treatments but needs more research for standard use.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.

Understanding how acne develops in different diseases could lead to new treatments.

Adenosine receptors could be promising targets for treating inflammatory skin diseases like psoriasis.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

CXXC5 can both suppress and promote cancer, making it a complex target for treatment.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.