research Regulation of Involucrin Gene Expression
Involucrin gene expression is controlled by specific proteins and signaling pathways.
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630-660 / 1000+ resultsresearch Bimatoprost in the Treatment of Eyelash Hypotrichosis
Bimatoprost is effective for growing longer, thicker, and darker eyelashes.
research Topical Spironolactone in the Treatment of Evaporative Dry Eye Disease
Spironolactone may help improve symptoms and tear quality in dry eye disease.
research Glucocorticoid Effect on Hair Growth Initiation: A Reconsideration
Steroids stop hair growth temporarily but don't block the signals that start it.
research Recent Advances in the Molecular Mechanisms Determining Tissue Sensitivity to Glucocorticoids: Novel Mutations, Circadian Rhythm, and Ligand-Induced Repression of the Human Glucocorticoid Receptor
New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.
research Primary Generalized Glucocorticoid Resistance And Hypersensitivity
The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.
research Effect of Thioredoxin Reductase 1 on Glucocorticoid Receptor Activity in Human Outer Root Sheath Cells
Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.
research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function
Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.
research Epithelial Cells in the Hair Follicle Bulge Do Not Contribute to Epidermal Regeneration After Glucocorticoid-Induced Cutaneous Atrophy
Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.
research A Variant of the Glucocorticoid Receptor Gene Is Not Associated with Adrenal Androgen Excess in Women with Polycystic Ovary Syndrome
The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.
research Disrupted Pancreatic Exocrine Differentiation and Malabsorption in Response to Chronic Elevated Systemic Glucocorticoid
High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.
research AKR1D1 Regulates Glucocorticoid Availability and Glucocorticoid Receptor Activation in Human Hepatoma Cells
AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
research Hair Glucocorticoid Levels in Parkinson’s Disease
People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.
research Novel Insights Into the Molecular Mechanisms Underlying Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
research Recent Advances in the Molecular Mechanisms Causing Primary Generalized Glucocorticoid Resistance
Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
research When Can I Stop My Steroids? The Patient Perspective on Glucocorticoid Usage in Adult Inflammatory Myopathy
Patients need better information about the risks of long-term steroid use.
research EP03: An Audit of Glucocorticoid Prescription in Patients with Giant Cell Arteritis
Many patients with Giant Cell Arteritis did not follow their steroid treatment plans properly.
research Hair Growth Promoting Effects of Geranium Sibiricum L Extract on Human Dermal Papilla Cells Under Glucocorticoid-Induced Stress Condition
Geranium Sibiricum L extract may promote hair growth by increasing growth factors and decreasing inhibitory factors under stress.
research Glucocorticoid-Induced Side Effects Cause Oral Lesions in Systemic Lupus Erythematosus: A Case Report
Glucocorticoid treatment in lupus can cause oral lesions, which need early diagnosis and comprehensive care.
research The Glucocorticoid Resistance Syndrome: Two Cases of a Novel Pathogenic Variant in the Glucocorticoid Receptor Gene
A new gene variant causes glucocorticoid resistance in a mother and son.
research A Case of Glucocorticoid Resistance Syndrome
The patient likely has Chrousos syndrome, a rare condition causing insensitivity to glucocorticoids, requiring high-dose dexamethasone treatment.
research Perceived Predation Risk Predicts Glucocorticoid Hormones, But Not Reproductive Success in a Colonial Rodent
Prairie dogs with fewer neighbors are more stressed but their number of babies isn't affected.
research Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor
Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.
research Generalized Glucocorticoid Resistance
Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.
research Skin and Glucocorticoids: Effects of Local Skin Glucocorticoid Impairment on Skin Homeostasis
Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.
research Study of Fecal Glucocorticoid Metabolite in Bears: A Review
Analyzing bear poop helps measure their stress without harming them.
research Long-Term Glucocorticoid Use and The Skin
Long-term glucocorticoid use can cause skin problems like easy bruising and poor wound healing, especially at higher doses.
research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene
A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
research An Extraordinary Stroke
Untreated congenital adrenal hyperplasia can lead to complications like stroke and needs glucocorticoid treatment.
research Current and Future Perspectives on Clinical Management of Classic 21-Hydroxylase Deficiency
Treating classic 21-hydroxylase deficiency requires precise glucocorticoid dosing and attention to individual patient needs, with new treatments showing promise.