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Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Micropigmentation is a widely accepted tattooing technique for hiding cosmetic issues and medical uses, with permanent results and few side effects, but risks infection if not done with sterile tools.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Bimatoprost is promising for treating some types of hair loss but needs more testing for androgenetic alopecia.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Adrenal disorders can cause lasting brain and behavior issues in children.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Feed restriction in sheep leads to finer wool fibers but may reduce wool quality.

Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.

Capecitabine is as effective as intravenous treatments with fewer side effects, but requires careful management of Hand-foot syndrome and patient education.

Low-level laser therapy effectively treats female hair loss, increasing hair count by 51%.

IGF-1 increases whisker growth in transgenic mice.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

The document concludes that terbinafine is effective for treating scalp fungal infections in children and recommends not excluding them from school during treatment, while also highlighting the need for updated treatment guidelines due to changing infection patterns.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Skin diseases, especially psoriasis, greatly affect people's quality of life, similar to chronic diseases.

Male cancer patients have a higher risk of severe illness and death from COVID-19 than female patients.

Signaling pathways are crucial for hair growth in goats.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.