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The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

A gene variation is linked to hair thickness in Asians.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Scientists found cells in hair that are key for growth and color.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Hormonal therapies are safe and effective for treating adult women's acne.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Some alternative treatments for hair loss might work, but more research is needed.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Micropigmentation is a widely accepted tattooing technique for hiding cosmetic issues and medical uses, with permanent results and few side effects, but risks infection if not done with sterile tools.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.