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Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Goat reproductive activity and coat growth are affected by light and temperature, with temperature altering prolactin levels and hair growth, but not melatonin or estrus onset.

Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Silicon can improve skin and hair health, but more research is needed.

Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.

Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.