86 citations,
March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
64 citations,
June 2009 in “Photomedicine and Laser Surgery” Excimer light effectively treats various skin diseases, including psoriasis, vitiligo, and mycosis fungoides.
54 citations,
May 2018 in “International journal of risk & safety in medicine” Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.
49 citations,
March 2018 in “Toxicological sciences” Low doses of mixed chemicals cause permanent reproductive malformations in male rats.
41 citations,
February 1970 in “Archives of Dermatology” Oral contraceptives can cause skin issues like dark patches, acne, yeast infections, sensitivity to light, spider veins, skin rashes, and hair loss.
34 citations,
February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
29 citations,
December 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.
26 citations,
December 2016 in “Psychiatric Clinics of North America” Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.
22 citations,
March 2019 in “Environmental health” Higher fluoride levels may delay puberty in boys.
14 citations,
January 2013 in “Indian Journal of Endocrinology and Metabolism” Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.
10 citations,
October 2019 in “Acta Pharmaceutica” Medicinal plants are used to treat skin conditions, but more evidence is needed before recommending them widely.
5 citations,
July 2019 in “Nutrients” Low selenium intake may delay puberty in boys but not in girls.
4 citations,
August 2021 in “Pediatrics in review” DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.
3 citations,
September 1999 in “Journal of the European Academy of Dermatology and Venereology” People with Behçet's disease can develop life-threatening lung artery aneurysms that may require surgery.
1 citations,
April 2022 in “Emergency Medicine Australasia” The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.
1 citations,
December 2010 in “Elsevier eBooks” Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.
1 citations,
June 2008 in “The Journal of Urology” Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.
Most postmenopausal women experience significant skin changes and various skin conditions.
June 2023 in “The journal of sexual medicine” The treatment helped a transgender woman stop drinking, improved her mental health, and reduced her gender dysphoria.
December 2013 in “Reactions Weekly” Some men taking finasteride for hair loss experienced anxiety, depression, and sexual problems, which sometimes continued after stopping the medication.
April 2022 in “The Journal of Urology” Men may experience long-term sexual dysfunction after stopping Finasteride.
June 2021 in “Reactions Weekly” Finasteride caused serious side effects and led to six suicides.
46 citations,
October 2012 in “Seminars in reproductive medicine” Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
6 citations,
March 2009 in “Annals of Saudi Medicine” Finasteride use during early pregnancy may cause limb deformities in babies.
15 citations,
March 1997 in “International Journal of Dermatology” Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.
297 citations,
December 2005 in “Journal of controlled release” P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
2 citations,
August 2020 in “JCRPE” A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.
53 citations,
June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
34 citations,
July 2020 in “Dermatologic Therapy” Searches for acne, hair loss, and eczema increased during COVID-19, while searches for other skin issues decreased.
22 citations,
April 1998 in “Dermatologic Clinics” Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.