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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Early hair loss may indicate risk of insulin resistance.

Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Aromatase gene variation may increase female hair loss risk.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Effective management of children's hair loss involves accurate diagnosis, various treatments, and supportive care.

There's no significant link between the D19S884 marker at the insulin receptor gene and polycystic ovary syndrome.

Genetic variations in hair keratin proteins exist but don't significantly affect hair structure.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Some congenital hair disorders improve in childhood or with treatments like minoxidil and retinoids, while others like Netherton syndrome and trichothiodystrophy have a poor prognosis.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

Eyebrow loss has many causes and requires accurate diagnosis for proper treatment.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.