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A new genetic mutation in mice causes permanent hair loss and skin wrinkling.

In this study, researchers investigated genetic variants in pharmacogenes affecting tadalafil and finasteride pharmacokinetics, finding fed volunteers had higher drug exposure than fasting individuals, but genetic variation did not significantly impact pharmacokinetics after correcting for multiple comparisons.

This study found that individuals in this Egyptian cohort carrying the leucine (L) allele of the 5-α reductase type II enzyme had a higher risk of developing androgenetic alopecia, which may be associated with oxidative stress.

In this study, the CYP 21A2 gene p.V281L mutation was associated with an increased susceptibility to familial frontal fibrosing alopecia, suggesting an antigen-driven mechanism linked to certain human leukocyte antigen haplotypes.

This study identified eight mutations in five genes associated with different aspects of ichthyosis among Tunisian patients, enhancing understanding of its genetic and clinical diversity.

In this study, researchers evaluated hair follicle transplantation techniques and reported that challenges such as limited follicle supply and low follicle survival rates often limit patient satisfaction, but advances in regenerative medicine may offer promising new solutions.

This review highlights the role of the APCDD1 gene and associated pathways in hair follicle biology, offering new perspectives on genetic contributors to hair loss and suggesting potential avenues for developing targeted treatments and preventive strategies.

This review highlights recent advancements in understanding and treating alopecia, emphasizing genetic and immune factors involved in different forms, and discusses emerging therapies such as gene-editing and exosome-based treatments, though achieving complete hair regrowth remains a challenge.

This review summarizes 15 years of clinical and experimental research advancements in hidradenitis suppurativa, highlighting its recognition as a uniquely healable inflammatory skin disease but reports no new clinical results.

This review discusses varying views on the pathogenesis of hidradenitis suppurativa and the challenges in achieving a consensus, emphasizing the need for further research rather than providing new findings.

This review discusses various perspectives on the pathogenesis, classification, and contributing factors of hidradenitis suppurativa and reports no new experimental results; the authors call for further studies to advance understanding and treatment.

This review discusses genetic and nutritional causes of hair loss, highlighting that around 90% of treated men show noticeable hair regrowth with a dual inhibitor, while women's hair loss may improve by correcting iron and l-lysine deficiencies.

This review discusses the potential causes and treatments for alopecia in nonhuman primates, emphasizing the need for comprehensive testing before attributing hair loss to stress.

This article reviews various causes and treatments for alopecia, including nutritional deficiencies, stress, and hormonal changes, and reports no new clinical results.

This study found that hair shaft miniaturization in aging and genetic hypotrichosis leads to hair follicle stem cell loss through mechanical compression and apoptosis mediated by the Piezo1 channel.

This review discusses various genetic and acquired conditions associated with poliosis circumscripta and reports no new clinical results.

In this retrospective review, the author discusses key discoveries in understanding androgen excess disorders like PCOS, focusing on genetic and molecular insights gained from 1965 to 2015.

This article discusses the causes of polycystic ovary syndrome, including environmental pollutants, genetics, and oxidative stress, and explains how these factors contribute to symptoms like irregular menstrual cycles and obesity without reporting new clinical results.

This review highlights that managing androgenetic alopecia in women involves a variety of treatments including approved drugs like minoxidil, as well as newer therapies such as PRP and LLLT, yet emphasizes the need for more research on long-term outcomes and treatment standardization.

This review discusses various management strategies for androgenetic alopecia in women, including approved drugs like minoxidil and emerging therapies such as PRP and LLLT, highlighting the need for research on long-term outcomes and standardization.

This study identified multiple factors associated with the onset of androgenetic alopecia, including age, occupation, education, mental status, genetic history, and dietary habits, with mental factors being significant.

This study found that female pattern hair loss may be influenced by genetic factors and hormonal changes, particularly in young adults, and identified specific dermoscopic features associated with the condition.

In this study, combining medical treatments, natural remedies, dietary guidance, and stress management achieved the best outcomes for hair regrowth and patient satisfaction in Cambodia, highlighting the importance of a multifaceted approach for effective hair loss prevention and treatment.

This study reviewed current and investigational treatments for alopecia areata, finding that novel therapies can improve patients' quality of life, though more research is needed to explore the genetic causes and develop targeted treatments.

This review discusses the genetic basis of woolly hair syndrome and its potential link to heart disorders, highlighting recent discoveries of new molecular pathways and suggesting possible future treatment options.

This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.

This review identifies genetic mutations associated with congenital hair loss disorders in Japanese populations, particularly highlighting common LIPH gene mutations linked to woolly hair/hypotrichosis, and reports no new clinical results.

The abstract discusses the multidisciplinary nature and advancement of dermatology and aesthetic procedures within the health sciences, emphasizing the integration of diagnostic, corrective, preventive, and therapeutic approaches, but does not provide specific study results.

This report describes two unusual cases of frontal fibrosing alopecia in men, highlighting potential vaccine-related immune triggers and genetic factors, especially regarding the pronounced facial papular phenotype observed.