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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The book "Plastic Surgery, 2nd Edition" is a valuable, comprehensive resource for plastic surgeons.

A group has developed therapies that show promise for treating cancer and various other conditions.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Early treatment of acne is crucial to prevent scarring and psychological effects.

Long COVID causes various long-term health issues and needs better awareness and treatment.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Certain fungi and bacteria help orchid seeds germinate and plants grow better.

Severe COVID-19 may cause hair loss, and doctors recommend supplements and topical treatments to manage it.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Finasteride may increase the risk of suicide or severe self-harm in men with mood disorders but not in the general population.

High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.

Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.

The black orchid Brasiliorchis schunkeana produces chemicals that attract certain insects and have potential antimicrobial properties.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.

Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.

The new rodent model successfully mimics non-lean human PCOS symptoms.

Recognizing and managing central sensitization and stress is crucial for treating chronic pain.

Women may need different blood pressure guidelines than men for heart disease prevention.

Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.