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The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Skin fat helps with body temperature control and has other active roles in health.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The hair follicle is a great model for research to improve hair growth treatments.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Genetic variations affecting skin structure play a key role in severe acne.

Using steroids can increase the risk of heart problems.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.

Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

Both human and animal-derived small extracellular vesicles speed up skin healing equally well.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.

The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.

Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

pH changes are crucial for root hair growth because they affect enzymes and proteins that control the cell wall and growth.

CD61 is important for mouse tooth cell growth and works through Lgr5.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.