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Human skin can make serotonin and melatonin, which help protect and maintain it.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

The Rotterdam Study aims to understand various diseases in older adults.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Skin fat helps with body temperature control and has other active roles in health.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Certain genes control the color of human hair by affecting pigment production.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Some common medications can harm male fertility, but many effects can be reversed.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.