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Tofacitinib may help treat severe hair loss, but more research is needed.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Liposomes could improve how skin care products work but are costly and not very stable.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Choosing the right model order in brain connectivity analysis can affect the detection of differences between healthy individuals and those with seasonal affective disorder.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

Finasteride may cause slight depression and anxiety.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.