47 citations,
July 1967 in “Science” Not eating enough protein can cause hair roots to shrink and lose color, and hair to become thinner.
46 citations,
January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.
26 citations,
November 1968 in “The Lancet” Malnourished Andean Indian children had abnormal hair roots compared to healthy children.
25 citations,
May 2016 in “Progress in Biophysics & Molecular Biology” R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
24 citations,
November 1978 in “Biochemistry” α-type filaments in guinea pig hair follicles have unique structural features.
21 citations,
April 2011 in “Physiological Research” Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.
20 citations,
August 2014 in “Therapeutic delivery” The transfollicular route shows promise for noninvasive, targeted drug delivery but needs more research.
12 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.
10 citations,
January 2010 in “International Journal of Trichology” Synthetic hair fibers for hair restoration were controversial in 2009 due to health risks and lack of support from the International Society of Hair Restoration.
7 citations,
March 2017 in “Medical Hypotheses” Aquaporins could be new drug targets for treating polycystic ovary syndrome.
7 citations,
November 2003 in “Current Opinion in Obstetrics & Gynecology” Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.
6 citations,
May 1987 in “Acta dermato-venereologica” Syphilis patients showed abnormal hair root changes, with no difference between primary and secondary stages.
5 citations,
August 2012 in “Journal of Dermatology” Tamoxifen may cause female hair loss by increasing androgen receptor expression.
4 citations,
July 2001 in “Personality and Individual Differences” Men with moderate hair loss had the best spatial thinking, and long-term DHT might affect cognition.
3 citations,
November 2019 in “Journal of Investigative Dermatology” Adenosine helps human hair grow and prevents hair loss by targeting specific cells.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
September 2018 in “Cosmetics” Inositol and arginine solutions improve hair follicle health and turnover.
April 2017 in “International journal of research in Ayurveda and pharmacy” Ayurvedic methods can help reduce the harmful effects of chemicals in cosmetics.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Iron deficiency is not more common in women with hair loss, and neurogenic rosacea may need different treatment.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
April 2017 in “Journal of Investigative Dermatology” Higher leptin levels link to hair loss.
January 2014 in “Journal of Pharmaceutical Negative Results” Liquorice and Indian jujube root extracts don't help in fighting male pattern baldness.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
466 citations,
August 2004 in “Journal of the American Academy of Dermatology” Rosacea is a skin condition with unclear causes, classified into four subtypes.
369 citations,
June 2013 in “Biochimie” Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
200 citations,
November 1997 in “Planta” Calcium affects where root hairs grow, but other unknown factors determine their growth direction.
193 citations,
February 2015 in “Nature Communications” Fungi-produced compounds can change plant root growth.
182 citations,
December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
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September 2010 in “Molecular & cellular proteomics” Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.