31 citations
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February 2014 in “Journal of dermatological science” This study found that placental growth factor (PlGF) enhanced hair shaft elongation and accelerated hair follicle growth, suggesting its potential as a therapeutic target for alopecia.
80 citations
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April 2011 in “Plant physiology” This study suggests that the GPX-PDE1 and GPX-PDE2 genes in white lupin enhance root hair development and contribute to Pi limitation acclimation by facilitating glycerophosphodiester degradation.
January 2011 in “Journal of Human Genetics” This study found a severe MBTPS2 gene mutation in a Japanese IFAP syndrome patient, suggesting other factors may influence the syndrome's clinical features compared to previously studied patients.
July 2024 in “Journal of Investigative Dermatology” PP405 may help hair growth by activating hair follicle stem cells.
2 citations
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March 2016 in “The Journal of Dermatology” The researchers reported that the facial Psoriasis Log-based Area and Severity Index (fPLASI) more reliably and sensitively captured clinical improvement in facial psoriasis than the existing facial Psoriasis Area and Severity Index (fPASI).
January 2011 in “Journal of Diagnosis and Therapy on Dermato-venereology” This study found that female pattern hair loss may be influenced by genetic factors and hormonal changes, particularly in young adults, and identified specific dermoscopic features associated with the condition.
January 1999 in “American Journal of Medical Genetics Part A” This case report describes a rare occurrence of ectodermal dysplasia features in a 14-year-old with MBTPS1 gene variants, expanding the known spectrum of related disorders.
May 2025 in “Dermatology Reports” In this case study from King Fahad University Hospital, an 11-month-old Saudi boy with a history of short, non-growing hair was diagnosed with autosomal recessive woolly hair/hypotrichosis, attributed to a homozygous mutation in the LIPH gene.
January 2013 in “Scholarworks (University of Massachusetts Amherst)” This dissertation reveals that FERONIA, a cell wall-binding receptor kinase, plays a crucial role in regulating plant functions such as sugar signaling, pollen tube reception, and RAC/ROP-mediated auxin signaling.
2 citations
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March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” This study strongly suggests that a distinct form of hereditary localized alopecia in a Chinese family is linked to a novel locus on chromosome 2p25.1–2p23.2.
8 citations
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June 2022 in “Scientific Reports” Using a transgenic pig model, this study demonstrated that LGR5 is a marker of hair follicle stem cells across different species, with important similarities and differences in gene expression and developmental processes.
January 2013 in “edoc (University of Basel)” This study found that TRF1 plays a crucial role in maintaining pluripotency and stem cell compartments, but it is not a suitable in vivo telomere length marker.
October 2023 in “Journal of dermatological science” This study highlights that mutations in the MBTPS2 gene can lead to dermatological disorders like IFAP syndrome and severe bone diseases such as X-Linked Osteogenesis Imperfecta, emphasizing the significance of understanding these genetic variants for disease mechanisms and associations.
8 citations
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June 2004 in “Journal of Investigative Dermatology” Certain peptides can prevent hair loss in young rats caused by a cancer drug.
April 2019 in “Journal of Investigative Dermatology” This study found that DPP4 is significantly involved in matrix deposition and fibrosis in human skin fibroblasts, although the exact functions of DPP4 remain unclear.
This study found that the FER/MLO signaling module plays a crucial role in calcium oscillations and ROS production in root hair tip growth, with the MLO15 protein regulating these processes and restoring disrupted growth and signaling in fer mutant root hairs.
January 2025 in “Dermatology Research and Practice” In this research, RNA expression analysis of scalp biopsies from lichen planopilaris patients revealed changes in specific genes after treatments with hydroxychloroquine, narrow band UVB, or low level laser light therapy, suggesting potential biomarkers and implicating M2 macrophages in the disease's immunopathogenesis.
26 citations
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May 2016 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that mice lacking sPLA2-IIE had distinct skin abnormalities, particularly affecting hair follicles, highlighting the differing roles of sPLA2 isoforms in mouse skin.
28 citations
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January 2012 in “International Journal of Trichology” This study observed that specific trichoscopic features like white peripilar signs, scalp pigmentation, and focal atrichia are associated with advanced female pattern hair loss in Fitzpatrick skin type III patients.
July 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study developed a potent Wnt surrogate with high specificity for the Fzd7 receptor in mice, promoting full hair follicle regeneration and robust hair growth, suggesting potential applications in tissue development and targeted regeneration.
June 2026 in “Springer Link (Chiba Institute of Technology)” This study found that fibroblast growth factors exhibit significant expression differences in the skin of rodents and primates, which may be linked to their evolutionary and environmental adaptations.
1 citations
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April 2016 in “The American Journal of the Medical Sciences” This article discusses the characteristics of lichen planus pigmentosus and frontal fibrosing alopecia but reports no new clinical findings; the authors review existing knowledge.
4 citations
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December 2013 in “British Journal of Dermatology” This study reports an association between the ESR2 gene variant rs10137185 and female-pattern hair loss in German patients.
11 citations
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April 2012 in “Journal of Investigative Dermatology” A specific mutation in PA-PLA1α causes abnormal hair growth.
4 citations
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August 2013 in “Expert Review of Dermatology” This review discusses recent advances in the diagnosis and management of female pattern hair loss but reports no new clinical results.
32 citations
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February 2008 in “Journal of the American Academy of Dermatology” This case report describes a family with autosomal dominant transmission of keratosis follicularis spinulosa decalvans, with observed treatment refractoriness in multiple topical and systemic therapies.
1 citations
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April 2018 in “Journal of Investigative Dermatology” This study found that FZD2 is crucial for hair follicle formation and postnatal growth in mice and has a novel role in regulating early epidermal development, including stratification and cornification.
1 citations
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January 2022 in “European Journal of Pharmacology” In this study, FMN was found to inhibit androgen receptor function and androgen-regulated gene expression in prostate cancer cells, suggesting potential as an antiandrogen therapy.
126 citations
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April 2006 in “International Journal of Dermatology” This study found that frontal fibrosing alopecia and lichen planopilaris have similar histopathological features, but FFA exhibits more prominent apoptosis and less inflammation with spared interfollicular epidermis.