17 citations
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May 2020 in “Forensic Science International Genetics” This study found that genetically variant peptides from human hair can reliably identify individuals despite differences in age and storage conditions, provided environmental and processing factors are controlled.
November 2001 in “PubMed” This research found that perming, combing, and stretching cause hair damage, leading to a significant reduction in keratin levels within a specific molecular weight range.
This study found that perming, combing, and stretching human hair lead to damage, as evidenced by a reduction in keratins with molecular weights between 67,000 to 43,000 daltons.
This study suggests that keratin peptide signatures in human hair shafts may potentially be used to distinguish gender and ethnicity, although further validation with larger samples is needed.
This study suggests that keratin peptide signatures from human hair shafts could potentially distinguish gender and ethnicity, though confirmation in larger studies is needed.
December 2025 in “Rapid Communications in Mass Spectrometry” This study found that pepsin digestion was more effective than trypsin at identifying keratin-associated proteins in human hair shafts and confirmed that trypsin introduced a bias in the analysis of protein composition that pepsin can correct.
June 2025 in “Rapid Communications in Mass Spectrometry” In this study, researchers developed a simplified and reliable method to prepare human hair shaft samples, achieving over 75% protein extraction efficiency and improved keratin sequence coverage, with the approach showing high reproducibility across different labs and operators.
22 citations
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January 2020 in “PeerJ” This study suggests that keratin peptide signatures in human hair shafts could potentially be used to distinguish gender and ethnicity, though further research on a larger scale is needed.
December 2022 in “Kristu Jayanti Journal of Core and Applied Biology (KJCAB)” This study examined the morphometric features of hair from different regions of India to identify potential regional characteristics.
This study found considerable variation in hair shaft proteomic profiles among Caucasian, African-American, Kenyan, and Korean subjects, with individual and site-specific differences observed.
10 citations
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May 2018 in “Forensic Science International” This study concluded that the process of mummification disfigures facial features, making identification challenging, but commercial shrunken heads retain more defining features compared to ceremonial ones.
9 citations
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February 2018 in “Forensic Science International” This study investigated the identity of Victor Vinnetou as Mbuyisa Makhubu using forensic facial comparison and DNA testing, but the findings were inconclusive, requiring further investigation.
5 citations
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September 2016 in “Security science and technology” DNA can predict physical traits like eye and hair color accurately, especially in Europeans, but predicting other traits and in diverse populations needs more research.
2 citations
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March 2023 in “Research Square (Research Square)” This review discusses existing forensic DNA phenotyping panels for biogeographical ancestry and externally visible characteristics and highlights major technical limitations, including terminology issues, genetic knowledge gaps, and technological debates; it reports no new results.
11 citations
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February 2019 in “Research and reports in forensic medical science” This article discusses the use of forensic DNA phenotyping to infer physical characteristics from biological samples without a reference sample, aiding investigations but raising ethical and legal concerns.
27 citations
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March 2022 in “Forensic Toxicology” This review discusses micro-segmental hair analysis for forensic toxicology, emphasizing its potential to provide detailed drug distribution profiles and its application in investigations, while noting the method's limitations and future perspectives.
27 citations
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April 2011 in “International journal of legal medicine” This study reports that the completeness of DNA degradation in hair during cornification varies among individuals and affects the success rates of forensic hair DNA analysis.
383 citations
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February 2011 in “Nature Reviews Genetics” This review discusses advances in forensic DNA profiling, highlighting new genetic markers and methods for identifying unknown individuals, but reports no new research findings.
16 citations
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April 2011 in “Journal of The American Academy of Dermatology” This article overviews dermatologic findings in forensic pathology and reports no new results; it emphasizes the importance of recognizing skin manifestations in identifying types of injury.
March 2026 in “Egyptian Journal of Forensic Sciences” This review critically examines Forensic DNA Phenotyping, highlighting high accuracy in predicting certain traits but also legal and ethical challenges, particularly around regulatory fragmentation and issues of genetic privacy.
This paper discusses advancements in forensic hair analysis, emphasizing a novel DART–HRMS method that improves the accuracy and efficiency of detecting drug use timelines.
January 2014 in “Sen'i Gakkaishi” This study highlights that dyeing and other processing methods can impact the identification of animal species from hair fibers using an amino acid sequence analysis technique.
1 citations
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January 2023 in “International journal of all research education and scientific methods” This review highlights how forensic drug analysis in hair using modern instrumental techniques offers advantages such as easy sample collection and chronological tracking of drug use, emphasizing its value for law enforcement and other applications.
December 2025 in “International Journal For Multidisciplinary Research” This review highlights that microscopic analysis of human scalp hair remains crucial in forensic science for crime scene investigations, despite limitations such as subjectivity and potential misidentification, and notes that integrating DNA analysis and digital imaging could enhance accuracy.
46 citations
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January 2009 in “Textile Research Journal” This study presents a DNA-analytical method that can reliably identify and differentiate cashmere, fine wool, yak, and camel hair fibers in both untreated and processed samples.
226 citations
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January 2002 in “Biological and Pharmaceutical Bulletin” This study developed a rapid method to extract proteins from human hair, revealing phosphorylation on serine and threonine residues in alpha-keratins and matrix proteins.
89 citations
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April 2023 in “Forensic Science International Genetics” This review summarizes advancements in forensic DNA phenotyping for appearance, ancestry, and age prediction from crime scene samples, reporting no new research findings but highlighting areas needing further research and validation.
4 citations
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March 2024 in “Forensic Sciences Research” This review found that current forensic DNA phenotyping panels for biogeographical ancestry and visible traits face significant limitations due to inconsistencies in terminology, genetic understanding, and genotyping technologies, highlighting the need for harmonization and further research.
15 citations
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January 1987 in “Electrophoresis” This study found that electrophoretic keratin typing of head hair can identify specific polypeptide patterns, suggesting potential applications in genetic and forensic investigations.
4 citations
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September 1999 in “Journal of Clinical Forensic Medicine” Caffeine in hair might help identify people, but it's not always reliable.