Recent Advances in Forensic DNA Phenotyping of Appearance, Ancestry, and Age

April 2023 in “ Forensic Science International Genetics ”

Manfred Kayser, Wojciech Branicki, Walther Parson, Christopher Phillips

Forensic DNA Phenotyping hair structure hair loss massively parallel sequencing

Studysummary This review summarizes advancements in forensic DNA phenotyping for appearance, ancestry, and age prediction from crime scene samples, reporting no new research findings but highlighting areas needing further research and validation.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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research Genetic Prediction of Male Pattern Baldness Based on Large Independent Datasets

3 citations , November 2022 in “European Journal of Human Genetics”

This study developed new genetic prediction models for male pattern baldness with improved accuracy by utilizing a large set of markers and independent datasets, making them the most reliable available for this trait.

research Epigenetic Age Estimation in Saliva and Buccal Cells

19 citations , August 2022 in “Forensic Science International Genetics”

This study developed and validated tissue-specific and age prediction models using epigenetic markers, achieving up to 83.69% correct classification for tissue origin and a median absolute error of ±3.66 years for age estimation.

research Exploring the Possibility of Predicting Human Head Hair Greying from DNA Using Whole-Exome and Targeted NGS Data

37 citations , August 2020 in “BMC Genomics”

This study found that while genetic variants contribute minimally to predicting hair greying in a Polish population, age remains the primary predictor, underscoring the complexity of hair greying as a genetic trait.

research Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness

58 citations , December 2018 in “Nature Communications”

This study found that male pattern baldness in European males is strongly heritable and associated with genetic markers linked to earlier puberty, bone density, and pancreatic function.

research Genome-Wide Association Meta-Analysis of Individuals of European Ancestry Identifies New Loci Explaining a Substantial Fraction of Hair Color Variation and Heritability

94 citations , April 2018 in “Nature Genetics”

This study identified more than 100 genetic loci associated with hair color variation in Europeans, explaining a significant portion of the trait's heritability and advancing understanding of hair pigmentation.

research Genetic Prediction of Male Pattern Baldness

133 citations , February 2017 in “PLoS Genetics”

In this study, researchers used genetic data from over 52,000 men to identify over 250 genetic loci associated with severe hair loss and developed a predictive algorithm for determining hair loss risk.

research A Genome-Wide Association Scan in Admixed Latin Americans Identifies Loci Influencing Facial and Scalp Hair Features

196 citations , March 2016 in “Nature Communications”

In this study, researchers identified 18 genetic associations with scalp and facial hair traits in Latin Americans, including novel loci for hair greying and balding, with implications for understanding hair evolution.

research Prediction of Male-Pattern Baldness from Genotypes

37 citations , October 2015 in “European Journal of Human Genetics”

This study found that a genetic model using SNPs can predict early-onset male-pattern baldness with moderate accuracy, which may assist in decisions about interventions.

research Evaluation of the Predictive Capacity of DNA Variants Associated with Straight Hair in Europeans

36 citations , September 2015 in “Forensic Science International: Genetics”

This study found that specific DNA variants in the TCHH, WNT10A, and FRAS1 genes are associated with predicting straight hair in Europeans, showing high sensitivity but low specificity, especially using a neural networks approach.

research Evaluation of DNA Variants Associated with Androgenetic Alopecia and Their Potential to Predict Male Pattern Baldness

48 citations , May 2015 in “PLOS ONE”

This study found that a genetic test using 5 to 20 SNPs can predict male pattern baldness with variable accuracy in European men, especially those aged 50 and older.

research Improving Human Forensics Through Advances in Genetics, Genomics, and Molecular Biology

383 citations , February 2011 in “Nature Reviews Genetics”

This review discusses advances in forensic DNA profiling, highlighting new genetic markers and methods for identifying unknown individuals, but reports no new research findings.