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Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Polymeric nanoparticles show promise for treating skin diseases.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Androgens can both increase and decrease hair growth in different parts of the body.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Targeted cancer therapies often cause serious skin problems that need careful management.

Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.

Researchers created human hair follicles using a new method that could help treat hair loss.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Too much androgen can cause hair loss; finasteride may help.