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Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Stress can stop hair growth in mice, and treatments can reverse this effect.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

The conclusion is that certain scalp tissue changes are characteristic of lichen planopilaris, with mucinous perifollicular fibroplasia being a new feature for diagnosis.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

FFA's causes may include environmental triggers and genetic factors.

Msx2 and Foxn1 are both crucial for hair growth and health.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Genetics and hormones cause hair loss; finasteride treats it safely.

Improving the environment and cell interactions is key for creating human hair in the lab.

Chemotherapy can cause permanent, non-reversible hair loss similar to pattern baldness.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

Prolactin slows down hair growth in mice.

Human skin cells can create new hair follicles when transplanted into mice.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.