11 citations,
September 2010 in “American Journal of Medical Genetics - Part A” A Turkish family with sparse hair and eyebrow loss has a mutation in the U2HR gene linked to Marie Unna hereditary hypotrichosis.
44 citations,
November 2009 in “Archives of Dermatology” CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
January 2017 in “Open Journal of Endocrine and Metabolic Diseases” The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.
September 2024 in “Journal of Family Medicine and Primary Care” Primary health physicians in Saudi Arabia need better guidelines for treating hair loss with vitamins and minerals.
6 citations,
January 2015 in “Biochemical Society Transactions” The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.
3 citations,
December 2016 in “PubMed” Menstrual abnormalities in PCOS women may not greatly affect their metabolic and hormonal profile.
May 2009 in “South African Family Practice” The author believes that giving medical conditions official names can sometimes overwhelm or scare patients.
17 citations,
June 2017 in “Gene” A rare genetic mutation found in an Indian family can be detected through prenatal screening.
8 citations,
January 2009 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” A specific thyroid hormone resistance mutation may be linked to different types of hair loss.
7 citations,
July 2014 in “BMJ case reports” A rare skin disorder, Ichthyosis with confetti, has no cure but treatment focuses on managing symptoms with moisturizers.
January 2015 in “Journal of North Sichuan Medical College” July 2007 in “Cancer biology & therapy” Removing a key gene in mice leads to premature aging and loss of stem cells.
26 citations,
July 2012 in “Journal of family planning and reproductive health care” The document says that hirsutism in women usually needs hair removal and hormone treatment to manage symptoms and improve well-being.
32 citations,
February 2008 in “Developmental dynamics” Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.
30 citations,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
132 citations,
August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
14 citations,
January 2018 in “Endocrine” Cantú syndrome may be linked to pituitary adenomas.
October 2023 in “Journal of Family Medicine and Primary Care” More awareness and education on iron deficiency anemia are needed in Riyadh.
59 citations,
July 2015 in “Journal of Immunology” Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
218 citations,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
November 2012 in “South African Family Practice” The article concludes that early treatment of alopecia is crucial to prevent permanent hair loss.
20 citations,
January 1998 in “Dermatology” Newborn acne may be linked to family history of high male hormone levels.
7 citations,
September 2019 in “Journal of Cellular Physiology” Akt2 protein is essential for normal cell division in early mouse embryos.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
December 2023 in “Journal of family medicine and primary care” Many people in Saudi Arabia experienced hair loss after COVID-19, especially women, those treated with antivirals, and those with a history of hair shedding.
3 citations,
March 2022 in “Korean Journal of Family Medicine” Doctors should consider SLE in males even if antinuclear antibody tests are negative.
November 2024 in “Journal of Family Medicine and Primary Care” 5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.
8 citations,
December 2021 in “International Journal of Family Studies, Food Science and Nutrition Health” Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.
2 citations,
November 2022 in “Skin research and technology” 5% topical minoxidil improves hair density and quality in monilethrix patients.