Correlations of the Onset of Androgenic Alopecia with Family History and Serum Dihydrotestosterone Levels in 614 Female Patients

    December 2024 in “ Chinese Journal of Dermatology
    TLDR Higher DHT levels and family history lead to earlier hair loss in women.
    The study analyzed 614 female patients with female androgenetic alopecia (FAGA) to assess the impact of family history and serum dihydrotestosterone (DHT) levels on the age of onset. Results showed that patients aged 20-30 had significantly higher DHT levels compared to healthy controls, but these levels normalized with age. A positive family history was associated with an earlier onset age (24.61 years) compared to those without a family history (25.64 years), although no correlation was found between family history and DHT levels. Elevated DHT levels were linked to a younger age at onset and consultation, but not to the duration of the disease.
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