TLDR A specific gene mutation causes monilethrix in this family, and minoxidil treatment improves hair condition.
The study conducted by Wang Xia and published in the Chinese Journal of Dermatology in 2019 focused on a family of Han nationality with monilethrix, a rare hair disorder. The research involved mutation analysis of the type II hair keratin gene. The findings identified specific genetic mutations associated with the condition, contributing to a better understanding of the genetic basis of monilethrix in this population. This study provided valuable insights into the hereditary nature of the disorder and highlighted the importance of genetic analysis in diagnosing and understanding hair-related diseases.
59 citations,
June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
43 citations,
December 2013 in “Seminars in Cell & Developmental Biology” Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
41 citations,
November 2011 in “The Journal of Dermatology” Some hair loss disorders are caused by genetic mutations affecting hair growth.
2 citations,
January 2013 in “Elsevier eBooks” The document explains the genetic causes and characteristics of inherited hair disorders.
1 citations,
February 2013 in “InTech eBooks” Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
26 citations,
December 2011 in “Journal of Investigative Dermatology” New gene identification techniques have improved the understanding and classification of inherited hair disorders.
