68 citations
,
April 2012 in “Journal of Investigative Dermatology” The study reports that Fgf18 and Tgf-β2 signaling pathways in hair follicle stem cells have opposing effects on the timing of hair cycle transitions, influencing the shift from telogen to anagen phases.
14 citations
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March 2016 in “Regenerative Biomaterials” This article proposes a broad interpretation of tissue engineering as systematically controlling the body's cells, matrices, and fluids, suggesting many existing therapies may fall under this category.
2 citations
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October 2023 in “Science advances” In this study, researchers demonstrated that human hair follicle outer root sheath cells release ATP, serotonin, and histamine in response to mechanical stimulation, which subsequently activates surrounding sensory neurons.
April 2018 in “Journal of Investigative Dermatology” This study found that Anigozanthos Flavidus flower extract may improve skin elasticity and reduce wrinkles by increasing essential extracellular matrix proteins in both in vitro and in vivo settings.
4 citations
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January 2026 in “Cell Discovery” This study introduced the concept of spatiotemporal clocks to understand how different phases of mammalian wound healing are coordinated, with a focus on the spatial domains and oscillatory molecular signals involved, while highlighting the potential for regenerative therapeutic strategies.
62 citations
,
January 2000 in “Developmental dynamics” This study found that Notch-related genes, including Notch1 and Notch2, and their ligands and regulators, have distinct patterns of expression during mouse hair vibrissa follicle development and the adult hair cycle.
3 citations
,
April 2021 in “PLoS ONE” The authors concluded that controlling voltage, pulse width, and calcium concentration in pulse electric field-activated platelet-rich plasma enhances the release of growth factors and serotonin without causing clot formation, suggesting potential clinical advantages over bovine thrombin-activated PRP.
9 citations
,
October 1989 in “Australian Journal of Agricultural Research” This study found that infused mouse epidermal growth factor induced wool follicle involution through a quasi-physiological process similar to catagen and a separate pathological action, resulting in fleece 'break' or shedding.
5 citations
,
January 2016 in “Hair therapy & transplantation” In this study, miliacin combined with polar lipids significantly stimulated IGF1 production, increased the renewal of keratinocytes, and enhanced collagen thickness in a hair follicle model.
45 citations
,
August 1992 in “PubMed” In this study, researchers found that changes in the extracellular matrix components, particularly fibronectin, laminin, and type IV collagen, during the rat vibrissa follicle growth cycle, suggest dynamic remodeling related to dermal-epidermal signaling.
1 citations
,
December 2024 in “Journal of Orthopaedic Research®” In this study, researchers developed a novel method combining in silico and in vitro techniques to discover Aromoline, a potential osteoarthritis treatment that increases type II collagen expression in chondrocytes by targeting the dopamine receptor D4.
This study found that hair follicles in mouse skin use common activator/inhibitor signals to maintain cyclical hair growth across different regions, with varying dynamics influenced by distinct anatomical domains.
2 citations
,
January 1990 1 citations
,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified lymphatic vessels as crucial components of the hair follicle stem cell niche, coordinating connections and contributing to hair follicle regeneration in mice.
19 citations
,
August 2022 in “Plant Signaling & Behavior” This article reviews how calcium and reactive oxygen species gradients and oscillations interact to promote root hair cell expansion and reports no new experimental findings.
82 citations
,
March 2016 in “Cell” This review highlights various methods of stem cell communication that reflect the unique organization and function of different tissues and reports no new results.
29 citations
,
September 2020 in “Polymers” This study found that electrospun poly(ε-caprolactone)/poly(3-hydroxybutyrate) blend fibers demonstrated nanometric dimensions and promising properties for drug delivery, with curcumin release linked to fiber morphology and processing parameters.
67 citations
,
February 1994 in “Developmental dynamics” This study analyzed the distribution of adhesion molecules and extracellular matrix components in human fetal skin, suggesting their roles in hair follicle development.
35 citations
,
July 2015 in “Journal of Theoretical Biology” This study introduced a theoretical model suggesting that the morphological transition from bud to cap in tooth germ development is driven by mechanical interactions among cells.
7 citations
,
August 2009 in “Applied Mathematics and Mechanics-English Edition” This study demonstrates that (9+2) topological patterns derived from fractal fiber sets exist, with nine total patterns and only two being independent or fundamental.
20 citations
,
July 1988 in “Clinics in dermatology” This article reviews the current practices and interpretations of research data on permanent waving and hair straightening, but does not present any new research findings.
October 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study reviewed existing literature on Androgenetic Alopecia treatments, finding that minoxidil promotes hair growth but can cause side effects due to its traditional formulations. Novel delivery systems like film-forming sprays may reduce these side effects and enhance efficacy.
85 citations
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January 2018 in “Cell stem cell” This study found that synchronized signals in the microenvironment regulate stem cell lineage choices in hair follicles by influencing chromatin dynamics during regeneration.
March 2026 in “Collagen and Leather” This study found that a newly developed supramolecular FPC hydrogel effectively promotes wound healing through its anti-inflammatory and angiogenic properties, making it a promising material for wilderness first aid due to its storage convenience, sprayability, and ability to speed up wound recovery.
July 2023 in “AYUSHDHARA” This article examines the Ayurvedic perspective on the aging process, detailing how physical, emotional, and metabolic changes occur naturally over time, affecting various body systems, and highlights the role of Vayu dosha during the final stage of life, Vriddhavastha.
8 citations
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September 2024 in “International Journal of Molecular Sciences” This review discusses how polymers can be customized to develop biomaterials that mimic the extracellular matrix, exploring their potential in biomedical and biotechnological applications by triggering cell functions similar to natural physiological systems.
8 citations
,
December 2003 in “Materials Research-ibero-american Journal of Materials” Polyquaternium 7® builds up on hair, improving its look and feel, and AFM is good for measuring these changes.
April 2018 in “Journal of Investigative Dermatology” This study found that Fgf20 signaling facilitates fibroblast migration and influences dermal condensate cell development during hair follicle morphogenesis by supporting cellular activities such as cell cycle exit and specific cell shape adoption.
December 2025 in “JURNAL PIJAR MIPA” This study found that a natural hair tonic spray formulated from 15% water pumpkin fruit extract promoted rabbit hair growth to a degree comparable to a synthetic control.
May 2026 in “Journal of Controlled Release”