2 citations
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May 2020 in “Journal of visualized experiments” This study describes a protocol for inducing endogenous reactive oxygen species in mouse skin, which stimulates tissue regeneration and promotes burn healing and hair follicle growth.
January 2024 in “Editora Científica Digital eBooks” This study highlights the therapeutic benefits of photobiomodulation, which uses light exposure to facilitate tissue repair and prevent inflammation and apoptosis, in treating conditions like arthritis, reumatism, and inflammatory pain, with its complex mechanisms potentially leading to future discoveries and treatments.
November 2025 in “Scientific Reports” This study found that a blink frequency of at least 20 blinks per minute is necessary to maintain tear film stability in young participants with dry eye symptoms, with lower frequencies significantly worsening various indicators of eye dryness.
19 citations
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February 2018 in “Lasers in Medical Science” This study found that 655-nm red light with LED enhanced hair shaft elongation and reduced catagen transition in human hair follicles in vitro by activating the Wnt/ß-catenin signaling pathway.
January 2015 in “Dermatology Review” This study found that LED light therapy may stimulate skin regeneration and wound healing, with various wavelengths affecting fibroblast proliferation, collagen synthesis, and hair growth in experimental settings.
47 citations
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October 2015 in “Dermatologic surgery” This review discusses the applications of the 308-nm excimer laser in treating various dermatologic conditions and suggests treatment is generally well tolerated, but calls for larger long-term studies.
2 citations
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September 2014 in “PubMed” This review discusses low-level laser or light devices as an alternative treatment for androgenetic alopecia and highlights the need for further research to compare their efficacy with existing therapies.
May 2023 in “Elsevier eBooks” This study found that low-level laser/light therapy is effective and safe for treating mild to moderate androgenetic alopecia in individuals with certain skin types, especially when combined with other treatments, although further research is needed to refine protocols and verify long-term outcomes.
March 2024 in “Chinese Chemical Letters” In this study, researchers demonstrated that zero valence fluorescent gold nanoclusters can be biosynthesized in damaged skin and inhibit hair follicle regeneration by affecting the NFκB inflammatory response pathway, suggesting potential as a treatment for hypertrichosis related to skin injury.
1 citations
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January 2015 in “Hair transplant forum international” This review discusses low level laser therapy for hair loss but reports no new research findings; it serves as an introduction to understanding existing knowledge before upcoming evaluations of recent studies.
June 2024 in “Advanced therapeutics” In this study, a novel hydrogel dressing combining photodynamic therapy with organic semiconductor nanoparticles and silk fibroin demonstrated effective antibacterial action and enhanced wound healing and hair follicle regeneration in a mouse model, showing promise as an advanced wound care solution.
6 citations
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April 2023 in “Frontiers in Bioengineering and Biotechnology” In a murine burn wound model, this study found that an enhanced fractal self-pumping dressing significantly reduced wound area and tissue edema by efficiently draining excess exudates.
9 citations
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November 2021 in “PubMed” This study found that FDA-approved low-level light/laser therapy devices significantly increased hair density in individuals with pattern hair loss compared to sham devices.
10 citations
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September 2022 in “Journal of Biophotonics” This study analyzed clinical and histological reports and concluded that blue light therapy is safe for human skin, with potential photoprotective effects against UV irradiation due to its impact on skin pigmentation mediated by Opsin-3.
January 2017 in “Lasers in Surgery and Medicine” This article introduces a special issue of "Lasers in Surgery and Medicine" focused on dermatology and plastic surgery, but it presents no new research findings.
5 citations
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September 2005 in “Dermatologic Surgery” This study reports that using LED polarized magnification in hair transplant recipient sites can reduce eye strain and improve ease of site creation, but offers no graft placement advantage over traditional methods.
September 2023 in “Journal of The American Academy of Dermatology” In this study, researchers evaluated how subjects perceive the effectiveness of three FDA-cleared photobiomodulation devices for home use in treating androgenetic alopecia, though specific outcomes or comparative effectiveness are not reported in the abstract.
2 citations
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March 2025 in “Archives of Dermatological Research” HEV light can harm or help skin and scalp, so safe exposure guidelines are needed.
In this research, low-fluence light-based hair removal was explored, revealing its potential for at-home use with improvements in efficacy and safety, particularly for dark skin individuals, although further studies are necessary.
1 citations
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July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses various topics from the 62nd Annual Montagna Symposium on the Biology of Skin, focusing on the diverse effects of light on skin biology, and reports no new clinical results.
6 citations
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August 1993 in “Archives of Dermatology” This study found that polymorphous light eruption (PLE) may include a wide range of conditions, requiring careful differentiation from similar skin disorders such as benign summer light eruption.
December 2022 in “IntechOpen eBooks” This source evaluates the clinical effectiveness of 308 nm monochromatic excimer phototherapy in treating moderate-to-severe alopecia areata, noting that both laser and lamp methods show promise without significant risks.
January 2026 in “Frontiers in Pharmacology” This study demonstrated that SHFKO significantly accelerated healing in acute radiation-induced skin injuries, with mechanisms involving apoptosis inhibition, suppression of inflammation, and restoration of ROS balance, suggesting its potential as a novel multi-target therapy for radiodermatitis.
January 2020 in “프로그램북(구 초록집)” This study found that using a low-level light therapy helmet device daily for 24 weeks improved hair density and thickness among participants, though it did not significantly impact sebum secretion or erythema index.
1 citations
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February 2023 in “International journal of research - granthaalayah” This study reports that electromagnetic energy from a hydrocolloid wound dressing paste adversely affected human skin lipid droplets in vitro, but the implications, including potential cancer links, are unknown.
16 citations
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April 2025 in “Journal of the American Academy of Dermatology” In this study, an expert panel established a consensus guideline indicating that photobiomodulation is a safe and effective treatment for various conditions, including peripheral neuropathy and androgenic alopecia.
April 2026 in “Frontiers in Medicine” This study observed that 675-nm diode laser therapy may serve as a safe and possibly effective adjuvant treatment for telogen effluvium, showing improvements in hair pull test results, pruritus, and trichodynia among patients. However, controlled studies are needed to confirm its efficacy.
November 2024 in “Dermatology Online Journal” This review found promising evidence for the efficacy of certain laser and light-based therapies in treating various forms of alopecia, such as low-level light therapy for androgenetic alopecia and excimer laser for alopecia areata, but emphasized the need for further understanding of these treatments.
June 2026 in “Frontiers in Medicine” This study evaluated the 308-nm excimer laser as an adjuvant treatment for frontal fibrosing alopecia and found it may stabilize hairline recession and improve erythema and perifollicular hyperkeratosis, with transient erythema as the only reported adverse effect.
January 2019 in “The Review of Laser Engineering” This study observed that multiphoton excitation microscopy revealed changes in vascular structure and hair papillae in mice subcutaneous tissue following cyclophosphamide treatment for chemotherapy-induced alopecia.