March 2026 in “International Journal of Advanced Biochemistry Research” This study investigated the hair of German shepherd dogs, revealing variations in color, shape, and band patterns across different body regions, while all hair types shared similar anatomical structures such as continuous, vacuolated medullas and cuticular scales with smooth or rippled margins.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that a proteomics-based approach can effectively distinguish between scalp and pubic hair by identifying unique protein signatures, providing a more quantitative and objective method for tracing hair contamination sources in GMP manufacturing and forensic investigations.
December 2019 in “Periodicals of Engineering and Natural Sciences (PEN)” This research reported that using J48 algorithms with bagging improves prediction accuracy of hair health through machine learning by analyzing factors like spatial-temporal images, gender, and age, achieving a real-time performance of 89.5%.
73 citations
,
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This article reviews the potential relationship between different forms of permanent hair loss such as cicatricial pattern hair loss and discusses related conditions, reporting no new clinical findings.
2 citations
,
May 2017 in “Journal of the American Academy of Dermatology” 51 citations
,
March 1990 in “Journal of Investigative Dermatology”
September 2022 in “JAAD case reports” This case study of a 45-year-old man from Tonga describes the identification of pachyonychia congenita through genetic testing, revealing a mutation in the keratin gene KRT16, associated with chronic painful skin and nail conditions.
11 citations
,
January 2018 in “Acta dermato-venereologica” In this study, researchers identified gremilin-2 as a highly specific gene to the dermal sheath cup, suggesting it plays a key role in maintaining its properties.
3 citations
,
September 2021 in “Experimental and Therapeutic Medicine” This study described the clinical characteristics of keratosis pilaris atrophicans faciei in 14 patients, noting that earlier diagnosis may enable more targeted treatment options.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, the Hamilton-Norwood subtype of female pattern hair loss was associated with early onset and polycystic ovary syndrome, while the Ludwig pattern was more common overall.
5 citations
,
June 2008 in “British Journal of Dermatology”
3 citations
,
June 2022 in “European journal of human genetics” This study reports the first cases of recessive KRT17-related pachyonychia congenita involving all ectodermal derivatives in seven members of two consanguineous Pakistani families.
4 citations
,
November 2016 in “The Journal of Dermatology” This study found that the weak tensile strength of pili torti hair may result from loose keratin intermediate filaments due to abnormalities in disulfide bonds.
January 2019 in “The Egyptian Journal of Hospital Medicine” In this study, researchers evaluated trichoscopic features in 500 Egyptian patients with patchy hair loss and found specific patterns, such as perifollicular scale with 90% sensitivity and 99.5% specificity, which effectively aid in diagnosing primary cicatricial alopecias.
7 citations
,
June 2017 in “Journal of Cutaneous Pathology” This study reports a case of cystic panfolliculoma, highlighting the role of epithelial-mesenchymal interactions in its pathogenesis and explaining its histological resemblance to trichofolliculoma.
28 citations
,
September 2013 in “European Journal of Histochemistry” This study demonstrates a varied distribution of keratins in the epidermis of the Malayan pangolin, suggesting evolutionary adaptations related to their distinctive scales.
126 citations
,
April 2006 in “International Journal of Dermatology” This study found that frontal fibrosing alopecia and lichen planopilaris have similar histopathological features, but FFA exhibits more prominent apoptosis and less inflammation with spared interfollicular epidermis.
2 citations
,
June 2013 in “Journal of Dermatological Case Reports” This article presents a case of Olmsted syndrome in a 5-year-old boy, adding to the limited number of reported cases of this rare keratinization disorder.
December 2002 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” This study investigated a potential link between male pattern baldness and Pityrosporum group fungal contamination but found no significant statistical association.
January 2025 in “Clinical Case Reports” This study reports a rare case of follicular porokeratosis in a diabetic woman, suggesting a potential association with diabetes mellitus in addition to its known presentation with keratotic papules and scalp alopecia.
January 1961 in “The Journal of Anthropological Society of Nippon” This study examined hair from a mixed-heritage family and suggested that variations in pigment formation significantly influence hair form, including the occurrence of twist-knots.
5 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” 53 citations
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June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews extensive genetic polymorphisms in the keratin-associated proteins of human hair, indicating complexity but reporting no new clinical results and calls for further research on their potential impact on hair structure.
2 citations
,
June 2019 in “International Journal of Dermatology” This study found that while a modified BASP classification for pattern hair loss could classify previously unrecognized types, it was less accurate and harder to use than the existing BASP classification.
30 citations
,
December 2017 in “Clinical, Cosmetic and Investigational Dermatology” This study found significant differences in hair density, non-vellus hair diameter, and percentage of miniaturized hair between normal women and those with female pattern hair loss, particularly in the midscalp and parietal areas.
16 citations
,
January 2015 in “Annals of Dermatology” In this study, trichoscopic features aiding differential diagnosis of alopecia in Korean patients were found to be similar to those in Caucasians, but pigment pattern frequencies differed due to racial characteristics.
26 citations
,
December 2015 in “Journal of The European Academy of Dermatology and Venereology” This article introduces a new grading system called the FPHL Severity Index to better identify and monitor early stages of female pattern hair loss using clinical criteria.
38 citations
,
February 2012 in “British Journal of Dermatology” This study suggests that the AR/EDA2R locus may contribute to early-onset female pattern hair loss, but no association was found with the 20p11 locus.
September 2023 in “Journal of the American Academy of Dermatology” This study found a high concordance between subject-reported and clinician-reported Fitzpatrick Skin Phototypes, but 14% of subjects misjudged their skin type, often overestimating it.
142 citations
,
August 2015 in “Arthritis & Rheumatology” This study found significant heterogeneity in transcriptome patterns among SSc patients, identifying prominent fibroinflammatory and keratin signatures that may aid in stratifying patients for targeted treatment approaches.