Keratosis Pilaris Atrophicans Faciei: An Observational, Descriptive, Retrospective Clinical Study

The study focused on Keratosis pilaris atrophicans faciei (KPAF), a hereditary follicular disorder characterized by follicular papules and hair loss on the eyebrows, with onset typically in early childhood. Conducted on 14 patients diagnosed between 2000 and 2020, the study aimed to identify common clinical characteristics to aid in earlier diagnosis. The mean age of diagnosis was 17.04 years, with initial symptoms appearing around 4.85 years. Progression included facial erythema and keratotic papules, leading to eyebrow hair loss by age 14. Patients often had other conditions like xerosis cutis and acne. The study highlighted the need for better understanding of disease progression and treatment, suggesting that early diagnosis could lead to more effective, individualized treatments such as topical emollients, systemic retinoids, or laser therapy.