2 citations
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January 2017 in “Journal of Biotechnology Research Center” This study found that hair dyes significantly affect DNA sequence analysis, with the organic extraction method performing better on hair shafts and the prepFiler kit yielding higher success for follicle-included samples.
October 2023 in “CRC Press eBooks” This chapter provides an overview of 11 common hair and nail conditions in children with brown skin, utilizing clinical photographs and a question-and-answer format to discuss conditions such as alopecia areata, telogen effluvium, and nail lichen planus.
41 citations
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January 1992 in “Journal of medical genetics” This study described seven male patients and six female carriers of keratosis follicularis spinulosa decalvans, highlighting distinct dermatological and ophthalmic markers including follicular hyperkeratosis and corneal dystrophy.
60 citations
,
December 2005 in “Biomedical Papers” This article reviews hair analysis for drug detection and its applications in various fields, but reports no new research findings, emphasizing the need to consider the method's complexities and potential pitfalls.
December 2010 in “CRC Press eBooks” January 2017 in “日本皮膚科学会雑誌” This study suggests that keratin peptide signatures from human hair shafts could potentially distinguish gender and ethnicity, though confirmation in larger studies is needed.
50 citations
,
December 2011 in “Skin Research and Technology” In this study, the researchers reported that their novel algorithm for hair restoration in dermoscopy images achieved high accuracy and texture preservation, outperforming other techniques in diagnostic accuracy and texture quality measures.
8 citations
,
January 2013 in “International Journal of Trichology” This study found that the BASP classification is an effective and easily remembered method for diagnosing and treating male and female pattern hair loss in the Indian population.
18 citations
,
December 1992 in “Journal of Cutaneous Pathology” This study observed that lectin-binding patterns in skin appendage tumors reveal differences in sweat gland tumors compared to normal tissues, but pilosebaceous tumors maintained a similar lectin-binding pattern to their corresponding normal structures.
10 citations
,
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study revealed that BMP5 in onychofibroblasts may play a key role in the differentiation of nail matrix keratinocytes, highlighting transcriptional similarities between nail and hair structures.
3 citations
,
February 2022 in “Journal of Dermatological Science” This study identified clinical features and genetic variants associated with early onset female pattern hair loss, highlighting decreased hair shaft density and specific SNPs related to androgenic features.
This study found that onychomatricoma can fully mimic the nail unit and differentiate toward the nail bed and isthmus, distinguishing it from other pilar tumors.
January 2025 in “International Journal of Trichology” In this 10-year study at a single hair referral center, pattern hair loss was the most common type of alopecia, affecting 67% of patients.
December 2021 in “Skin appendage disorders” This study developed and validated an objective dermoscopic severity score for evaluating female pattern hair loss, which may serve as a supplementary outcome measure in therapeutic trials.
February 2024 in “Clinical and Experimental Dermatology” This article discusses patterns of female pattern hair loss in men but reports no new clinical results.
61 citations
,
September 1994 in “Journal of Medical Genetics” This study found strong evidence linking a keratin gene anomaly to pachyonychia congenita, supporting its role in affecting skin, nails, hair, and mucosa.
18 citations
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March 2009 in “Experimental Dermatology” This study suggests that pilomatricoma can differentiate towards various hair follicle structures, including hair matrix, hair cortex, follicular infundibulum, outer root sheath, and hair bulge.
43 citations
,
September 2001 in “Scanning” Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.
44 citations
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August 1990 in “PubMed” This study provides evidence for K1 and K10 derivatives' presence in the inner root sheath and hair cuticle, suggesting that these hair follicle parts may follow familiar keratinization principles.
September 2024 in “Turkish Journal of Dermatology” In this study, researchers found that males with alopecia areata had a significantly lower 2D to 4D finger length ratio compared to healthy controls, suggesting this ratio might predict alopecia areata development, though it did not correlate with disease severity.
July 2026 in “Journal of Cutaneous and Aesthetic Surgery” This study found that trichoscopic quantitative parameters reliably indicate the severity of female pattern hair loss and complement the Sinclair scale by offering a more objective and reproducible grading system.
12 citations
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June 2013 in “The American Journal of Dermatopathology” This study reported that using photomnemonics facilitated accurate histopathologic interpretation of horizontal scalp sections in distinguishing between nonscarring and scarring alopecias by dermatopathologists and residents in a validation test.
88 citations
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June 2000 in “Journal of Investigative Dermatology” Keratin 17 is important for hair and nail structure and affects pachyonychia congenita symptoms.
7 citations
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November 2011 in “Skin Research and Technology” The authors observed that the patterned melanoderma on the hairless scalp of fair-skinned Caucasian men with androgenic alopecia resembled similar patterns seen on facial skin.
7 citations
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September 2019 in “Journal of The American Academy of Dermatology” This study found inflammation and fibrosis in both pattern hair loss cases and controls but concluded that these factors may not significantly contribute to the pathogenesis of pattern hair loss.
August 2023 in “Journal of Investigative Dermatology” This study using scRNA-seq on 96 skin biopsies from 51 healthy individuals revealed distinct cell signaling pathways in different skin sites, including unique pathways in facial and palmoplantar skin, which may explain their varying susceptibilities to skin disorders.
14 citations
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September 2019 in “Forensic Science International Genetics” This study found that hair shaft keratin proteins can be reliably identified from samples as small as 0.12 cm, suggesting their potential forensic utility with typical casework sample sizes.
September 2023 in “UCrea (University of Cantabria)” In this study, researchers found that mouse digits without nails could not regenerate after amputation, highlighting the necessity of nails for fingertip regeneration and suggesting a potential role for the Lmx1b gene in this process.
3 citations
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April 2011 in “Journal of the American Academy of Dermatology” This article describes a unique case of unilateral keratosis pilaris atrophicans faciei in a 19-year-old man, noting its clinical similarity to follicular mucinosis, but presents no new general findings.