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Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.

New antiscarring strategies show promise, including drugs, stem cells, and improved surgical techniques.

Human hair grows better in a special gel that mimics skin.

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

Hydrogel microcapsules help create cells that boost hair growth.

CTHRC1 helps hair grow back, and plantar dermis mixture boosts it.

Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.

Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.

Mesenchymal stem cell proteins in a special gel improved healing of severe burns.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.