May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The investigators highlighted Roota Hair Growth as a promising botanical solution for hair concerns, suggesting it may improve hair health by addressing the root causes of thinning, breakage, and scalp fatigue.
December 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” There are several promising treatments for hair loss, including dutasteride, latanoprost, ketoconazole shampoo, anti-androgens, laser/light treatment, and platelet-rich plasma, but more research is needed.
17 citations
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October 2017 in “Scientific reports” This study found that Super Merino sheep have a higher wool follicle density, finer fleece, and distinct gene expression compared to Small Tail Han sheep, which may inform future breeding and genetic interventions.
This study examined hair classification based on geo-racial origin, observing that Caucasian and Mediterranean hair differs morphologically from African or Asian hair, with differences in density, thickness, and fiber shape contributing to varied hair characteristics such as color and curliness.
December 2024 in “Veterinary Sciences” In this study of Zhexi Angora rabbits, researchers found that the fine-wool group exhibited lower fiber diameters and a higher hair follicle density than the coarse-wool group, and they identified key candidate genes potentially regulating wool quality through RNA-seq and genome resequencing techniques.
In this study, researchers used the CRISPR/Cas9 system to edit the FGF5 gene in Dorper sheep, observing increased density and finer wool, along with changes in cortisol levels and antioxidant enzyme activity linked to hair follicle development.
January 1994 in “Nihon Chikusan Gakkaiho” This study observed that mink dermal collagen fibrils undergo structural changes during the hair cycle, with increased fiber thickness and bundle density as minks grow.
August 2025 in “Scientific Reports” In this study, researchers observed that intractable pruritus in anterior chest keloid lesions is linked to increased intraepidermal nerve fibre density and elevated expression of substance P, without differences in Langerhans cells across different keloid regions.
January 2026 in “Frontiers in Animal Science” In this study, researchers assessed wool quality in sheep and found that the Gentile di Puglia breed, a Merino-derived Italian breed, exhibits finer wool through higher secondary follicle density compared to the non-merinized Sarda breed, suggesting its potential for sustainable wool production.
8 citations
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January 2016 in “Journal of fiber science and technology” This study found that cysteic acid generation during hair bleaching is diffusion-controlled, increasing with the square root of bleaching time, in both cuticles and cortex of human hair fibers.
April 2020 in “Research Square (Research Square)” This study found that melatonin treatment improved cashmere fiber quality and production in cashmere goats during the first growth cycle but had no effects in the subsequent cycle.
6 citations
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January 1989 In this study, synthetic hair implantation for small bald areas in patients with cicatricial or androgenetic alopecia showed varied results in hair density, durability, and complications over six months.
4 citations
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March 2016 in “Small ruminant research” This study examined vicuña skin and hair follicle structures, finding a high density of secondary hairs in fleece areas compared to belly and legs, and identified various types of cutaneous glands potentially important for chemical communication.
February 2025 in “BMC Genomics” This study found that in cashmere goats, melatonin treatments enhanced cashmere growth by stimulating secondary hair follicles, increasing follicle density, and improving yield and quality, highlighting key genes and metabolic pathways involved in this process.
September 2024 in “MedComm” This study by Bansaccal et al. found that skin with higher levels of type I collagen density and elasticity in the dermis can inhibit basal cell carcinoma development and spread by acting as a natural barrier against cell reprogramming in mice.
4 citations
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May 2024 in “Genes” Among Merino × Southdown cross sheep, this study found that certain variants of the KRT81 gene were associated with differences in fleece weight, but not with staple length or fibre diameter traits.
66 citations
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June 2004 in “Biophysical Journal” Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.
46 citations
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March 2019 in “Journal of Pineal Research” The study found that melatonin treatment in early postnatal cashmere goats increased both the quantity and quality of cashmere by promoting secondary hair follicle development and enhancing antioxidant enzyme activities.
This study found that single-born cashmere goats had higher birth weights, pre-weaning growth rates, and superior cashmere production attributes compared to twin-born goats, despite twin-born goats achieving compensatory growth post-weaning.
21 citations
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April 1990 in “Journal of comparative neurology” This study found that the spinal projection of afferents innervating slowly adapting mechanoreceptors had a greater rostrocaudal extent and number of boutons compared to those innervating rapidly adapting mechanoreceptors.
15 citations
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January 2012 in “International journal of trichology” This study found that the HairCheck® device, demonstrating high correlation between its Hair Mass Index and hair characteristics such as strand number and diameter, may be an effective tool for assessing hair mass changes in alopecia patients.
1 citations
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January 2011 in “Journal of Animal Science and Veterinary Medicine” This study found that injecting melatonin in female goats did not significantly affect follicle characteristics but did improve cashmere yield, potentially by enhancing secondary follicle growth and extending the cashmere growth period.
June 2025 in “Proceedings of the National Academy of Sciences” In this study, a mouse model with a PIK3CA gain-of-function mutation in Schwann cells revealed unique communication with neighboring cells and a glycolytic shift in peripheral nerves, and early alpelisib treatment significantly improved symptoms, though efficacy declined with delayed administration due to limited drug penetration.
August 2006 in “Experimental dermatology” This study found that nerve growth factor signaling in organ-cultured human hair follicles inhibits hair growth by inducing apoptosis-driven hair follicle regression.
117 citations
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November 2006 in “Experimental Dermatology” This review explores the biology of wool follicles and suggests their potential use as research models in modern biology, but it reports no new findings.
1 citations
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January 2020 in “VTechWorks (Virginia Tech)” This study found that early treatment with αCT1 in wound healing increased collagen synthesis and disorganization, potentially improving long-term scar appearance by altering early collagen matrix formation.
3 citations
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January 2017 in “PubMed” This report describes a case of inflammation and infection with specific pathogens in synthetic hair implants done by a non-medical professional, highlighting risks associated with the procedure.
3 citations
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February 2009 in “Chinese Journal of Traumatology (english Edition)” This study found that implanting microencapsulated dermal papilla cells in rat ears led to hair follicle regeneration, suggesting a potential alternative to fresh isolated dermal papillae for inducing hair growth.
24 citations
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December 2011 in “Journal of The American Academy of Dermatology” This study found that Caucasian female hair is denser than Asian female hair in the occipital region regardless of treatment but thinner in diameter in both the frontal and occipital regions.
61 citations
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April 2012 in “British Journal of Dermatology” This study analyzed changes in hair diameter and density with age in Caucasian women, highlighting variations in perception of hair amount over time.