38 citations
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February 2021 in “Journal of Investigative Dermatology” This review examines the complexities of age-related skin healing and discusses how translating findings from model organisms to humans could enhance understanding and treatment of impaired regeneration in aging populations, but it reports no new clinical results.
28 citations
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April 2024 in “Skin Research and Technology” This review concludes that platelet-rich plasma treatments significantly improve various facial skin parameters, particularly when combined with hyaluronic acid, and stresses the need for standardized preparation protocols.
28 citations
,
June 1995 in “The Journal of Dermatology” This study reports that flaky skin mice exhibit skin and nail features that closely resemble human psoriasis vulgaris, suggesting they may serve as a natural model for this condition.
27 citations
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January 2017 in “Indian Dermatology Online Journal” This study found no significant benefit from PRP injections for treating androgenetic alopecia in men, highlighting the need for larger, well-designed trials to assess its effectiveness and safety.
26 citations
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February 2022 in “Journal of pineal research” This review examines melatonin's potential effects on human skin and hair follicle pigmentation, highlighting the need to confirm findings from cell cultures in physiological tissue contexts.
25 citations
,
November 2012 in “Thermochimica Acta” This study found that lipid extraction increased water diffusion in wool and hair fibers; the effect was more pronounced in hair, indicating lipids are crucial for water permeability.
13 citations
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June 2020 in “Plastic and reconstructive surgery. Global open” This study found that preserving hair grafts in platelet-rich plasma before implantation significantly improved hair density, graft uptake, and hair thickness compared to saline preservation in hair transplantation patients.
8 citations
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September 2011 in “Scanning” This study found that multiphoton microscopy effectively visualizes the microstructure of in vivo mouse skin, offering a clear view of various skin layers and components like corneocytes and collagen fibers.
7 citations
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December 2018 in “Discoveries” This review discusses the potential benefits and limitations of platelet-rich plasma in wound healing, especially for skin wounds, and reports no new experimental findings.
5 citations
,
October 2023 in “International Wound Journal” In this study, a novel portable LED device significantly accelerated wound healing in rats, with faster wound closure, increased collagen deposition, and more microvessels at a higher radiation intensity, suggesting its potential for innovative wound management.
5 citations
,
February 2022 in “International Journal of Molecular Sciences” This review discusses the roles of distinct immune cell types in skin wound healing, highlighting findings from animal studies, but provides no new clinical results.
4 citations
,
January 2022 in “Transfusion Medicine and Hemotherapy” This review discusses the varied applications of platelet-rich plasma in plastic surgery and reports mixed evidence on its efficacy, indicating a need for more standardized, controlled trials.
2 citations
,
May 2021 in “European medical journal” This review reports that botulinum toxin is used in dermatology not only for treating rhytides but also for conditions like rosacea, hyperhidrosis, and menopause-related flushing, although its full safety and efficacy profile requires more research.
2 citations
,
September 2017 in “Plastic and Aesthetic Research” This study captured digital images of hair regions in healthy individuals and patients with androgenetic alopecia to analyze and compare the number of follicular units and hairs using software.
1 citations
,
March 2022 in “IntechOpen eBooks” This article reviews the functions and locations of skin stem cells and their role in regeneration and differentiation, relating age-associated skin changes to decreased stem cell functionality; it reports no new experimental findings.
1 citations
,
December 2017 in “Journal of clinical and investigative dermatology” This study reports on the clinical and dermoscopic diagnosis process for androgenic alopecia in patients at Zagazig University Hospitals but includes no new treatment findings.
1 citations
,
May 2016 in “Hair transplant forum international” This publication lists the contributors and affiliations for a research piece but reports no study results or findings.
August 2026 in “International Journal of Cosmetic Science” This study found that shed hairs from the root significantly outnumber broken hairs during hair fall, particularly in Chinese male and female participants, with shedding predominantly occurring during washing.
June 2026 in “JAAD reviews.” This review suggests that low-dose oral minoxidil may enhance hair density in certain nonandrogenetic alopecias, but highlights the need for controlled trials due to mixed and limited evidence.
May 2026 in “Skin Appendage Disorders” This study found that combining platelet-rich plasma with systemic therapies for androgenetic alopecia may result in greater improvements in hair density and width than using PRP alone, though the differences were not statistically significant.
February 2026 in “Bioengineering” This preliminary study suggests that hyperbaric oxygen therapy may improve scalp health and follicle activation in healthy adults, with subjective assessments showing significant improvements despite mixed objective findings.
February 2026 in “Preprints.org” In this preliminary study, HBOT appeared to improve subjective measures of hair and scalp health in healthy adults, but objective changes in follicle density and hair properties were not statistically significant.
November 2025 in “Journal of Clinical Medicine” This study found that a novel drinkable supplement significantly increased hair density and reduced hair shedding over six months in women with telogen effluvium, although the authors emphasize the need for larger, placebo-controlled trials to confirm these promising results.
November 2025 in “Phytomedicine” Modified Changfa Zirong Powder improves hair growth in androgenetic alopecia.
April 2025 in “Diagnostics” This review synthesizes data suggesting that managing inflammation and oxidative stress may enhance the effectiveness of PRP therapy for hair regeneration, though standardizing PRP protocols remains challenging.
February 2025 in “Cureus” This study focused on developing and validating standardized methods to reliably assess hair growth and scalp health in androgenetic alopecia, finding significant differences in hair parameters such as vellus and terminal hair counts, density, and thickness between affected and standardized areas.
February 2025 in “Journal of Tissue Viability” This scoping review suggests that physiological differences in skin structure may affect how individuals with different skin tones respond to pressure ulcer development, emphasizing the need for targeted prevention strategies.
January 2025 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia” In this study, researchers observed that telogen hair was more prevalent than anagen hair in both male and female agoutis over a one-year period in Teresina-PI, regardless of dry or rainy seasons, with no significant differences in dermal follicular volume between the sexes.
October 2024 in “Dermatologica Sinica” This study highlights the distinct distribution patterns of extracellular matrix components in the scalp skin of male and female androgenetic alopecia patients, with increased elastin staining intensity observed in male cases.
September 2023 in “Medicine” In this case report, a 41-year-old man with moderate androgenic alopecia showed an increase in hair density and improvements in hair characteristics after using Zimmer aqueous spray containing Zimmer herbal extract powder for 3 months, suggesting its potential as an alternative treatment for hair loss.