research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
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research Timing of Puberty in Relation to Semen Characteristics, Testicular Volume, and Reproductive Hormones: A Cohort Study
Men who went through puberty later had lower sperm counts and altered hormone levels, possibly affecting fertility.
research Contraception Care for Transmasculine Individuals on Testosterone Therapy
Transmasculine individuals on testosterone therapy need tailored contraception and fertility advice due to unique risks and benefits of each contraceptive method.
research Androgen Levels and Apoptosis in the Testis During Postnatal Development of Finasteride-Treated Male Rat Offspring
Finasteride treatment in male rats can reduce fertility and affect sperm development in their offspring.
research Detection of Cortisol, Estradiol, and Testosterone in Archaeological Human Hair from the Dakhleh Oasis, Egypt
Ancient hair can preserve hormones, revealing health and fertility insights.
research Testosterone Enhances Expression and Functional Activity of Epithelial Sodium Channel, Cystic Fibrosis Transmembrane Regulator, and Sodium Hydrogen Exchanger in Vas Deferens of Sex-Steroid Deficient Male Rats
Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.
research Connexin 43 Expression in the Testes During Postnatal Development of Finasteride-Treated Male Rat Offspring
Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.
research Supraphysiological Dose of Testosterone Impairs the Expression and Distribution of Sex Steroid Receptors During Endometrial Receptivity Development in Female Sprague-Dawley Rats
High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
research Clomiphene Citrate and Human Chorionic Gonadotropin Are Both Effective in Restoring Testosterone in Hypogonadism: A Short-Course Randomized Study
Clomiphene citrate is a cheap and simple treatment for low testosterone that works as well as human chorionic gonadotropin, alone or combined, especially for men who want to keep their fertility.
research The Effects of Finasteride on the Expression of Dazl, Tsga10, Sycp3, Prm2 Genes During Spermatogenesis in Testes of NMRI Mice
Finasteride, at doses of 5mg or higher, may negatively affect male fertility by reducing the expression of certain genes involved in sperm production.
research Common Urologic Diseases in Older Men and Their Treatment: How They Impact Fertility
Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.
research Fertility and Sterility Volume 101 Number 4, April 2014
The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.
research Geographical Differences in Demographics and Fertility Histories of Men Presenting for Infertility Evaluation Between the United States and Canada: Results from the Andrology Research Consortium
American men seeking infertility evaluation are generally older, more obese, have longer infertility duration, and different lifestyle habits compared to Canadian men.
research Is Age More Than Just a Number? Characteristics of Men Presenting for Reproductive Urology Fertility Evaluation in North America Stratified by Age Groups
Older men have different fertility histories and factors affecting fertility, suggesting they may benefit from earlier fertility evaluations.
research Testosterone Up-Regulates Vacuolar ATPase Expression and Functional Activities in Vas Deferens of Orchidectomized Rats
Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.
research Endocrinology and Auxology of Siblings with Non-Classical Congenital Adrenal Hyperplasia
Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.
research Physiological and Histological Study of the Effect of Finasteride Drug (Prostacare) on the Fertility of Albino Male Rats
Finasteride significantly reduces fertility in male rats.
research Finasteride and Male Fertility
Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.
research The Adverse Effects of Commonly Used Medications on Male Fertility: A Comprehensive Review
Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.
research The Effect of Finasteride on the Secretion of Testosterone, DHT, LH, FSH, and Tissue Factors in the Testis of NMRI Mice
Finasteride reduces sperm count and quality and alters hormone levels in mice.
research A Mutation of the Androgen Receptor Associated with Partial Androgen Resistance, Familial Gynecomastia, and Fertility
A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.
research Hormonal Control of Vas Deferens Fluid Volume and Aquaporin Expression in Rats
Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
research Salivary Testosterone Levels in Infertile Men
Men with low or no sperm count have lower salivary testosterone levels, and saliva testing can measure their testosterone well.
research Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male
The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
research Non-Classic Congenital Adrenal Hyperplasia
Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.
research New Insights Into Testosterone Biosynthesis: Novel Observations From HSD17B3 Deficient Mice
Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
research Reproductive System, Male: Biology of Spermatogenesis and Toxicology
The document explains how sperm cells are produced, the role of testosterone in this process, and how toxins can reduce sperm count and fertility.
research Effects of Testosterone on the Expression of Connexin 26 and Connexin 43 in the Uterus of Rats During Early Pregnancy
Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.
research Testosterone Down-Regulates Expression of αVβ3-Integrin, E-Cadherin, and Mucin-1 During Uterine Receptivity Period in Rats
Testosterone reduces key molecules needed for early pregnancy in rats.
research Androgens in SARS-CoV-2 Coronavirus Infections
Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.