October 2025 in “International Journal of Molecular Sciences” This study identified changes in immune activation, ferroptosis, and structural genes in alopecia areata subtypes, suggesting molecular markers that might help understand disease variability and guide future treatments.
February 2025 in “International Journal of Molecular Sciences” This study found that melatonin may enhance hair follicle stem cell viability by downregulating the nuclear receptor RORA, which otherwise inhibits cell proliferation and promotes apoptosis.
October 2024 in “BMC Genomics” This study examined the cytodifferentiation stage of hair follicle development in cashmere goats, identifying nine cell populations and key regulatory pathways, including transcription factors and keratin genes, that may influence fiber quality and inform breeding strategies.
March 2024 in “Biochimica et biophysica acta. Molecular basis of disease” This study found that deferoxamine may protect against sensorineural hearing loss by reducing oxidative stress-induced hair cell death through iron chelation and activation of the Nrf2 signaling pathway in lab models.
December 2023 in “Redox biology” In this study, DMC selectively eliminated senescent cells in old mice, prevented hair loss, improved motor coordination, and reduced senescence-associated secretory factors, suggesting its potential as a senolytic treatment.
May 2022 in “International Journal for Research in Applied Science and Engineering Technology” In this study, researchers explored the causes and treatment strategies for diffuse telogen effluvium, focusing on 60 patients with the condition linked to iron deficiency anemia, comparing the effectiveness of ferrous salts alone versus combined with Quilib lotion.
November 2018 in “Springer eBooks” Children need early diagnosis and treatment for iron-deficiency anemia to prevent learning problems and promote health.
October 2014 in “Transfusion Clinique et Biologique” This review discusses symptoms and syndromes associated with iron deficiency, with or without anemia, but reports no new clinical findings; the authors highlight the potential influence of intestinal factors on iron absorption.
research Iron
January 2014 in “Reactions Weekly” A woman had nausea and constipation from iron pills taken for hair loss due to low iron.
Iron supplements may reverse premature graying in iron-deficient individuals; ingrown nails are common in diabetics with certain risk factors; topical finasteride may reduce scalp DHT as effectively as oral finasteride; monilethrix treatment is challenging but some medications can help.
109 citations
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February 2018 in “CB/Current biology” This study concluded that the receptor-like kinase ERULUS, regulated by auxin, is crucial for modulating cell wall composition and pectin dynamics during root hair growth in Arabidopsis.
37 citations
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December 2020 in “PLANT PHYSIOLOGY” In this study, the researchers identified a temperature-sensitive mutant in Arabidopsis thaliana, showing disrupted root hair formation and altered responses to plant hormone treatments at elevated temperatures.
20 citations
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February 1968 in “Journal of Histochemistry & Cytochemistry” This study reports that citrulline, uniquely found in the inner root sheath of hair follicles, can be specifically detected with the carbamido diacetyl reaction, resulting in a bright orange color.
8 citations
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July 2022 in “Frontiers in plant science” This review outlines the current understanding of how pH contributes to root hair development and reports no new experimental findings.
This study found that the FER/MLO signaling module plays a crucial role in calcium oscillations and ROS production in root hair tip growth, with the MLO15 protein regulating these processes and restoring disrupted growth and signaling in fer mutant root hairs.
4 citations
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July 2018 in “International Journal of Research -GRANTHAALAYAH” This paper introduces a new microscopy technique to measure biomagnetic fields of human hair follicles using Prussian Blue Stain mixed with iron particles, but it reports no new clinical results.
3 citations
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August 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This study introduced a tabletop optical microscopy technique to measure the biomagnetic field reach of human hair follicles using Prussian Blue Stain with iron particles.
July 2020 in “Family Medicine” This review describes the role of iron deficiency in hair loss and explores the management of diffuse alopecia, emphasizing the potential of a new iron-based dietary supplement but reports no new clinical results.
This study found that exposure to Prussian Blue caused significant detachment of cuticle segments from the hair shaft in both new and aged human hairs.
April 2010 in “The FASEB Journal” This study found that knockout mice lacking intestinal hephaestin are smaller and anemic compared to wild-type, suggesting other mechanisms may compensate for iron absorption.
July 2026 in “Editora Pasteur eBooks” This narrative review explores current understanding and management of female pattern hair loss, highlighting the role of genetic and environmental factors, and discussing diagnostic approaches like trichoscopy alongside emerging therapeutic strategies.
1 citations
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January 2003 in “Benjamins eBooks” This study found no significant difference in hair cortisol concentrations between sows confined in farrowing crates and those in loose-housing systems, suggesting confinement may not affect chronic stress levels.
5 citations
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May 2018 in “Cancer Cell” This study found that melanoma cells develop resistance to therapies through dedifferentiation but become vulnerable to ferroptotic cell death, suggesting a potential therapeutic approach to target resistant forms of melanoma.
4 citations
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September 2012 in “Journal of Nanoscience and Nanotechnology” In this experimental study, there was no impact of the surrounding ferromagnetic film on the magnetization reversal processes in submicrometric antidot arrays, though a significant increase in coercivity was observed.
119 citations
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November 2014 in “Trends in Cell Biology” This review discusses the mechanisms and pathways of FGFR signalling and its roles in development, disorders, and therapeutic targeting, but reports no new clinical results.
2 citations
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June 2024 in “Frontiers in Plant Science” This study found that RALF peptides, through liquid-liquid phase separation, form condensates with pectin and other proteins, playing a pivotal role in plant development and stress response regulation.
2 citations
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April 2024 in “Molecular Plant” Auxin promotes root hair growth through oxidative processes involving reactive oxygen species.
December 2024 in “CONICET Digital (CONICET)” This study found that the small signaling peptide RALF22 plays a key role in root hair growth response to volatile compounds emitted by Penicillium aurantiogriseum through ethylene, auxin, and photosynthesis signaling in Arabidopsis.
17 citations
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August 2015 in “PLoS ONE” This study found that deferiprone significantly reduced dermal fibrosis and skin thickness in mice with chronic kidney disease treated with Omniscan, suggesting iron's role in gadolinium chelate toxicity and nephrogenic systemic fibrosis.
10 citations
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September 2023 in “Metabolites” This study reviews iron metabolism in the skin, highlighting how differentially expressed genes regulate iron recycling in the epidermis, and discusses changes in iron metabolism related to skin diseases.