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630-660 / 1000+ resultsresearch 42577 Application of the new clinical guidelines in frontal fibrosing alopecia of the male
This study examined the application of new clinical guidelines for diagnosing frontal fibrosing alopecia in 18 men, highlighting that current diagnostic criteria may often overlook early beard involvement and sideburn recession.
research Application of 2-Chloro-7-Nitrobenzo-2-Oxa-1, 3-Diazol (NBDCL) for Spectrophotometric Determination of Finasteride in Pharmaceutical Formulation
This study developed a new spectrophotometric method to accurately measure finasteride levels in pharmaceutical formulations using a reaction with NBD-CL.
research Validated RP-HPLC and TLC methods for simultaneous estimation of tamsulosin hydrochloride and finasteride in combined dosage forms
The researchers reported that they successfully developed and validated RP-HPLC and TLC methods for accurately measuring tamsulosin hydrochloride and finasteride in combination forms.
research Reflectance spectroscopy for noninvasive evaluation of hair follicle stage
This study introduced a noninvasive spectroscopy method to assess hair follicle stages in mice by measuring skin diffuse reflectance and melanin dynamics, offering a potential tool for hair regeneration research.
research Electrolysis and thermolysis for permanent hair removal
This review discusses the historical, legal, and clinical aspects of electrolysis and thermolysis, highlighting potential risks due to the lack of standardized training for electrologists in the United States, but reports no new clinical results.
research Determination of finasteride in healthy volunteers by optimized liquid chromatography-tandem spectrometry
This study successfully applied an optimized LC-MS/MS method for accurately determining finasteride concentrations and assessing its pharmacokinetics in healthy volunteers.
research 202 Automated assessment of tumor infiltrating lymphocytes informs mortality in thin melanoma
This study found that an automated tumor-infiltrating lymphocyte classification algorithm identified thin melanomas with less immune response, which were associated with higher mortality compared to other cases in the study.
research Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model
This study found that higher levels of the protein Flii were associated with enhanced hair follicle regeneration and longer hair fibers in a mouse model.
research E.L.F. square waves: a new therapy for androgenetic alopecia?
New therapy helps treat hair loss.
research Follicular Fluid: A Powerful Tool for the Understanding and Diagnosis of Polycystic Ovary Syndrome
This review discusses using human follicular fluid in metabolomic analysis as a diagnostic tool and predictor of success in assisted reproductive technology for PCOS patients, reporting no new results.
research Reproducibility package for an auditable exploratory re-analysis of miRNA dysregulation and aging-related validated target enrichment in female pattern hair loss
In this study, researchers conducted an exploratory re-analysis of miRNA dysregulation and aging-related target enrichment in female pattern hair loss using data from public GEO dataset GSE106780. The findings are preliminary and should be interpreted as candidate-level results due to the small sample size.
research Chemical Fingerprint and Quantitative Analysis for the Quality Evaluation of Platycladi cacumen by Ultra-performance Liquid Chromatography Coupled with Hierarchical Cluster Analysis
This study established a rapid and accurate ultra-performance liquid chromatographic method for chemical fingerprinting and analyzing Platycladi cacumen, effectively distinguishing batches based on geographical and climatic conditions.
research Mechanistic study of decreased skin penetration using a combination of sonophoresis with sodium fluorescein-loaded PEGylated liposomes with D-limonene
This study found that low frequency sonophoresis may reduce percutaneous absorption of sodium fluorescein-loaded liposomes by partially blocking follicular pathways in the skin.
research A New Histologic Pattern in 6 Biopsies From Early Frontal Fibrosing Alopecia
This study describes a newly observed "inflammatory vellus involvement" pattern in early frontal fibrosing alopecia, which may lead to misdiagnosis due to the absence of typical histological features.
research Formulation-by-Design of Efinaconazole Spanlastic Nanovesicles for Transungual Delivery Using Statistical Risk Management and Multivariate Analytical Techniques
This study optimized efinaconazole spanlastic nanovesicles using risk management and multivariate analysis for potential transungual delivery to treat onychomycosis, achieving improved drug permeability and dissolution efficiency.
research The structure of the cornified claw sheath in the domesticated cat (Felis catus): implications for the claw‐shedding mechanism and the evolution of cornified digital end organs
This study examined the complex morphology of the cornified claw sheath in domesticated cats, uncovering structures and growth patterns that help maintain sharp claw tips essential for climbing and prey capture.
research Symmetry of upper eyelid after unilateral blepharoptosis repair with minimally invasive conjoint fascial sheath suspension technique
This study found that minimally invasive combined fascia sheath suspension improved eyelid symmetry in patients with unilateral ptosis, particularly in measures of marginal reflex distance and eyelid contour.
research Hair Shaft Abnormalities. Pili Bifurcati: A Scanning Electron Microscopy Analysis
The study found that pili bifurcati causes hair to intermittently split into two branches, each with its own outer layer.
research Chromatographic method for clobetasol propionate determination in hair follicles and in different skin layers
This study developed and validated an HPLC-UV method for accurately quantifying clobetasol propionate in skin and hair follicles, demonstrating its application in in vitro permeation experiments.
research Transcriptome Profile at Different Physiological Stages Reveals Potential Mode for Curly Fleece in Chinese Tan Sheep
This study suggests that changes in expressed transcripts and splice isoforms may explain the transition from curly to straight fleece in Chinese Tan sheep as they age.
research Ultrahigh-Power Sonicator Lysis Enables Deep ProteomicProfiling of Hair Shafts for Fetal Growth Restriction Biomarker Discovery
This study developed a new method using ultrahigh-power sonication and mass spectrometry to improve protein extraction from hair shafts, identifying 239 differentially expressed proteins related to fetal growth restriction, which were validated as potential noninvasive biomarkers for perinatal diagnostics.
research Exploring murE protein inhibitors of Tropheryma whipplei through pharmacoinformatic approaches incorporating solubility-enhancing formulation insights
This study identified three Ayurvedic compounds that may serve as potential treatments against the macrolide-resistant enzyme murE of *Tropheryma whipplei*, addressing challenges in treating Whipple disease.
research DNA phenotyping: current application in forensic science
This article discusses the use of forensic DNA phenotyping to infer physical characteristics from biological samples without a reference sample, aiding investigations but raising ethical and legal concerns.
research An Automatic AI‐Based Algorithm That Grades the Scalp Surface Exfoliating Process From Video Imaging. Application to Dandruff Severity and Its Validation on Subjects of Different Ages and Ethnicities
This study evaluated a new AI-linked imaging device for grading dandruff severity, finding high correlation with expert assessments and suggesting its potential application in other skincare areas due to its versatility and ease of use.
research A Segmental Approach to Scoring Hair Density from Global Images: Introducing the Scalp Coverage Scoring Method for Clinical Trials and Practice
In this research, experienced clinicians noted inconsistency in the reproducibility of the commonly used Hamilton-Ludwig scales for assessing pattern hair loss severity in photographic assessments, leading to the proposal of a new 5-point scale for staging female hair loss.
research Hair removal using a pulsed-intense light source.
This study found that the Epilight multiple wavelength pulsed-intense light source was effective for long-lasting hair removal, particularly in individuals with dark hair and light skin.
research How to Prevent Follicular Transection During Strip Harvest: A Personal Technique
This abstract discusses the growing popularity of follicular unit extraction in hair restoration surgery but offers no clinical findings.
research Commentary on Elimination of Sweat Glands Using the Follicular Unit Excision Technique
The technique removes sweat glands effectively.
research Styling without shedding: Novel topical formula reduces hair shedding by contracting the arrector pili muscle
This study reports that a new topical solution, AB-102, containing a high concentration of a weak α1 agonist, significantly reduces hair shedding during brushing by up to 77% without causing cardiac or hemodynamic adverse events.