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    Glossary Fatty Acids

    long chains of carbon and hydrogen in fats (lipids)

    Fatty acids are essential building blocks of fats (lipids) that play a crucial role in the body. They are long chains of carbon atoms with hydrogen atoms attached, and they can be either saturated or unsaturated. These molecules are vital for energy storage, cell membrane structure, and signaling pathways.

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    1. Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development Proceedings of the National Academy of Sciences of the United States of America · 2003 · 93 citations
    2. Short-Chain Fatty Acids from <i>Cutibacterium acnes</i> Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes 2019 · 70 citations
    3. Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production Journal of Investigative Dermatology · 2019 · 40 citations
    4. Normal Fur Development and Sebum Production Depends on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands 2011 · 40 citations
    5. Fatty acids and related lipid mediators in the regulation of cutaneous inflammation Biochemical Society Transactions · 2018 · 28 citations
    6. Distribution of Glycolipid and Unsaturated Fatty Acids in Human Hair Lipids · 2014 · 18 citations
    7. GC–MS profiling and in silico prediction of MAPK receptor activation by fatty acids of watercress oil for hair growth marketed in Saudi Arabia Journal of Saudi Chemical Society · 2021 · 5 citations
    8. Effect of hair oils and fatty acids on the growth of dermatophytes and their in vitro penetration of human scalp hair. PubMed · 1970 · 4 citations
    9. Fatty acid composition of selected organs of gerbils maintained on a fat‐deficient or fat‐supplemented diet Lipids · 1977 · 4 citations
    10. Efficacy of a Nutritional Supplement, Standardized in Fatty Acids and Phytosterols, on Hair Loss and Hair Health in both Women and Men Journal of cosmetology & trichology · 2017 · 3 citations
    11. Para rubber seed oil and its fatty acids alleviate photoaging and maintain cell homeostasis International Journal of Cosmetic Science · 2024 · 1 citations
    12. Perturbations in fatty acid metabolism and collagen production infer pathogenicity of a novel MBTPS2 variant in Osteogenesis imperfecta Frontiers in endocrinology · 2023 · 1 citations
    13. Essential Fatty Acid Deficiency (EFAD) in a Patient with Vascular Ehlers Danlos Syndrome (EDS-4) (P12-053-19) Current developments in nutrition · 2019 · 1 citations
    14. Effects of Omega-3 polyunsaturated fatty acids on skin health, hair quality, and feeding behavior in adult Bichon Frises DOAJ (DOAJ: Directory of Open Access Journals) · 2026
    15. GC-MS Fatty Acid Profile and In silico Studies of Telfairia occidentalis Hook f. (Fluted Pumpkin) and Sphenostylis stenocarpa (African Yam bean) Seeds Oil on Human 5 Alpha Reductase II 2026
    16. ATOMISTIC CHARACTERIZATION OF HEALTHY AND DAMAGED HAIR SURFACES: A MOLECULAR DYNAMICS STUDY OF FATTY ACIDS ON PROTEIN LAYER ChemBioChem · 2024
    17. Exploring the effects of wetting and free fatty acid deposition on an atomistic hair fiber surface model incorporating Keratin Associated Protein 5-1 2022
    18. 694 Retinoid induced changes in the fatty acid profile of sebum and its effect on bacterial growth Journal of Investigative Dermatology · 2016
    19. The influence of non-esterified fatty acids (NEFA) on the ovarian production of androgens in a context of in vitro fertilisation (IVF) – preliminary results Fertility and Sterility · 2013
    20. In vivo and in vitro exposure to free fatty acids induce increased androgen production in animal models: a potential pathogenic factor of the polycystic ovary syndrome Fertility and Sterility · 2008
    21. Gut Microbiota Shapes the Effects of Saturated and Polyunsaturated Fatty Acids on Skin and Hair Follicle Homeostasis Journal of Investigative Dermatology · 2026
    22. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism bioRxiv (Cold Spring Harbor Laboratory) · 2026
    23. Dietary Vitamin D Supplementation Improves Hair Follicle Development and Affects Fatty Acid Metabolism in Rex Rabbits Food Science & Nutrition · 2025
    24. Immunohistochemical localization of fatty acid transporters and MCT1 in the sebaceous glands of mouse skin Institutional Repositories DataBase (IRDB) · 2016
    25. A Fatty Acid / Protein Complex in Human Hair Nature · 1961 · 19 citations
    26. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026
    27. Fatty acid oxidation fuels mitochondrial respiration to drive epidermal stem cell fate and differentiation Nature Communications · 2026
    28. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026
    29. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026
    30. Evaluation of Adipocyte Fatty acid Binding Protein (A-FABP) Serum Level in Male Androgenetic Alopecia Patients The Egyptian Journal of Hospital Medicine · 2024