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Did you mean Unsaturated Fatty Acids?

Glossary Unsaturated Fatty Acids

contain one or more double bonds in their hydrocarbon chains

Unsaturated fatty acids (UFAs) are a type of fat molecule that contains one or more double bonds between carbon atoms in their hydrocarbon chain. These double bonds create kinks in the chain, preventing the molecules from packing tightly together, which is why unsaturated fats are typically liquid at room temperature. They are considered healthier than saturated fats and are found in foods like olive oil, nuts, and fish.

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Research

5 / 1000+ results

research Gut Microbiota Shapes the Effects of Saturated and Polyunsaturated Fatty Acids on Skin and Hair Follicle Homeostasis

July 2026 in “Journal of Investigative Dermatology”

This study found that omega-6 and saturated fatty acid-enriched diets promote weight gain and certain skin changes regardless of gut microbiota, while omega-3 diets limit adiposity and affect skin in a microbiota-dependent way in mice, highlighting a diet–microbiota–lipid relationship in skin health.

research Multimodal Evidence of Mesostructured Calcium Fatty Acid Deposits in Human Hair and Their Role on Hair Properties

6 citations , September 2018 in “ACS applied bio materials”

This study provides conclusive evidence of exogenous calcium fatty acid deposits forming between the cuticle layers in hair, affecting its optical and mechanical properties.

research Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia

14 citations , October 2018 in “PloS one”

In this study, Far2-/- mice were observed to develop focal alopecia with altered sebaceous gland morphology and lower skin lipid levels compared to wildtype mice.

research Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity

47 citations , June 2012 in “Genes & Development”

This study found that maternal consumption of a western diet in mice led to toxic milk production, causing inflammation and alopecia in nursing neonates due to Toll-like-receptor activation.

research 752 Diet and the dermal white adipose tissue: Analyzing shifts in the cutaneous lipid landscape in response to dietary change

June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, mice fed various high-fat diets showed changes in dermal white adipose tissue lipid composition, with decreases in essential omega-3 fatty acids, which are important for skin health.

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community Adipocyte lipolysis activates epithelial stem cells for hair regeneration through fatty acid metabolic signaling

23 upvotes 10 months ago

Fatty acid metabolic signaling can activate epithelial stem cells for hair regeneration. Oleic and palmitoleic acids showed the best results, but practical application on humans remains uncertain.

community Topical serum made from monounsaturated fatty acids that triggered rapid hair growth in mice within 20 days

450 upvotes 5 months ago

A topical serum made from monounsaturated fatty acids showed rapid hair growth in mice within 20 days, but it remains experimental for humans. Users humorously discussed the frequent success of hair growth treatments in mice and expressed skepticism about translating these results to humans.

community Fats on your Head to Stop Hair Loss?

140 upvotes 2 years ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Do PUFA's accelerate hair loss? Is this tweet accurate?

4 months ago

PUFA foods like salmon and walnuts are healthy and do not accelerate hair loss. There is no evidence linking PUFAs to hair loss, and claims suggesting otherwise lack scientific support.

community Creatine effects on DHT Experiment

57 upvotes 2 years ago

Creatine might increase hair loss due to increased DHT sensitivity, but evidence is mostly anecdotal. The user is using oral minoxidil for hair loss and is cautious about starting creatine.

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