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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Fat cells help recruit healing cells and build skin structure during wound healing.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Latanoprost can make eyelashes longer, thicker, and darker.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Hair follicles may soon be used more for targeted and systemic drug delivery.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

PEVs improve minoxidil skin penetration, increasing hair growth.

Probiotic bacteria improved skin and hair health in aged mice.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.