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Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Hair loss linked to higher heart disease risk in both men and women.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

DHT may increase the risk of heart disease and death in elderly men.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.