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Using rodents for research shows that health problems in the womb can cause diseases later in life.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Belly fat is the main predictor of nonalcoholic fatty liver disease in both women with Polycystic ovary syndrome and healthy women.

Losing weight and eating better are key to managing metabolic syndrome and its related conditions.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Women with Polycystic Ovary Syndrome are more likely to have Non-Alcoholic Fatty Pancreas Disease, which is associated with older age, metabolic syndrome, insulin resistance, and high male hormone levels.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Aquaporins could be new drug targets for treating polycystic ovary syndrome.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Insulin resistance linked to obesity may increase COVID-19 severity.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.