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Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Mouse genital development depends on male or female hormones for specific features.

Hormones and stretching both needed for nipple area skin growth in mice.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

Lowering testosterone speeds up wound healing in male mice.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.