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390-420 / 1000+ resultsresearch Evolutionary Medicine: Perspectives on Human Development and Health Consequences in a Changing Environment. The 7th International Conference
This source describes the proceedings of the 7th International Conference on Evolutionary Medicine, summarizing over 100 scientific presentations focused on human development, health, and adaptation in changing environments, and commemorating Vilnius University's historical contributions to auxology and evolutionary medicine.
research Revolutionary Approaches to Hair Regrowth: Follicle Neogenesis, Wnt/ß-Catenin Signaling, and Emerging Therapies
This review explores emerging therapies for hair regrowth, highlighting two strategies: hair follicle neogenesis and Wnt/B-catenin pathway modulation, which show promise for treating alopecia by potentially offering more effective options than existing treatments.
research The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model
This study's model suggests that low androgen levels can increase selection for prostate cancer phenotypes resistant to hormonal therapy, potentially leading to more aggressive forms of cancer.
research The Polycystic Ovary Syndrome Evolutionary Paradox: a Genome-Wide Association Studies–Based, in silico, Evolutionary Explanation
This study suggests that variations in PCOS phenotypes observed across different ethnic groups may be due to a genetic gradient resulting from historical human migrations and genetic drift.
research Bioinformatics analysis of evolutionary characteristics and biochemical structure of FGF5 Gene in sheep
In this study, researchers found that the evolutionary and structural features of the oFGF5 gene in sheep may influence hair follicle development and hair growth regulation.
research Distribution of caspase‐14 in epidermis and hair follicles is evolutionarily conserved among mammals
This study reports that caspase-14's expression pattern in the epidermis and hair follicles is highly conserved across diverse mammalian species, suggesting its early evolutionary role in mammalian skin maturation.
research Hair Graying as an Evolutionary Checkpoint against Malignancy: a Stem Cell Perspective
Hair graying may help prevent cancer by protecting stem cells.
research LB1609 The evolutionary trajectory of primate skin appendage traits
This study found that humans have a much higher eccrine gland density than chimpanzees and macaques, suggesting a unique evolutionary path for human skin features.
research Androgenetic Alopecia: A Revolutionary Thermal Stress Model - DHT is Not the Culpritأ
This study suggests that male pattern baldness is primarily caused by heat stress in the brain rather than DHT toxicity, and personal experiments with menthol cooling have shown significant reduction in hair loss.
research Platelet-rich plasma - a revolutionary therapeutic option in multi-disciplinary indications
This review discusses the modern production methods, mechanisms of action, and various uses of platelet-rich plasma in medicine, highlighting promising applications but noting the need for more high-quality research.
research Comparative genomics analyses of alpha-keratins reveal insights into evolutionary adaptation of marine mammals
In this study, the researchers reported extensive gene loss and high pseudogenization rates of α-keratin genes in cetaceans compared to terrestrial mammals, likely linked to hair loss and aquatic adaptations.
research Why Mammal Body Hair Is an Evolutionary Enigma
This article explores the structure of mammal body hair and the challenges in explaining its evolutionary origins, reporting no new empirical findings.
research The Carnivore Follicular Integrity Framework (CFIF): An Evolutionary-Mechanistic Model of Hair Follicle Stability, Regenerative Peptide Biology (GHK-Cu), and Anti-Glycation Microvascular Protection
This theoretical research project proposes the Carnivore Follicular Integrity Framework, suggesting that animal-based diets may support hair follicle stability through various evolutionary and mechanistic pathways.
research The Carnivore Follicular Integrity Framework (CFIF): An Evolutionary-Mechanistic Model of Hair Follicle Stability, Regenerative Peptide Biology (GHK-Cu), and Anti-Glycation Microvascular Protection
This source provides supplementary materials for the Carnivore Follicular Integrity Framework, a theoretical model proposing that animal-based diets may support hair follicle stability through several biological mechanisms. The materials include definitions, nutrient tables, and mechanistic notes but do not report empirical results.
research The Carnivore Follicular Integrity Framework (CFIF): An Evolutionary-Mechanistic Model of Hair Follicle Stability, Regenerative Peptide Biology (GHK-Cu), and Anti-Glycation Microvascular Protection
This record provides supplementary materials for a theoretical model suggesting that animal-based diets may support hair follicle stability through various biological mechanisms, including regenerative peptides and anti-glycation protection.
research Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men
This study found that genetic predictions of male pattern baldness derived from European data do not accurately predict baldness in African populations, highlighting significant continental differences in genetic architecture and evolutionary history.
research Unique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins
This study found that keratins have evolutionarily conserved and domain-selectively enriched amino acids, which likely reflect their unique structural roles, with distinct patterns observed among epidermal, hair, and simple-type epithelial keratins.
research The solar window hypothesis: androgenetic alopecia as an evolutionary adaptation to maintain bone mineral density in vitamin D receptor low-efficiency variants
research Hair follicle differentiation: expression, structure and evolutionary conservation of the hair type II keratin intermediate filament gene family
This study characterizes a type II keratin intermediate filament gene family involved in early sheep follicle differentiation, detailing gene expression patterns and sequences in hair cortical cells.
research Understanding skin morphogenesis across developmental, regenerative and evolutionary levels
The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
research Modeling animal genomics in mice: An authentic approach for the functional interrogation of evolutionarily and agriculturally critical variants
This commentary highlights the potential of using transgenic and genome-edited mouse models to validate findings from livestock genomic and multi-omic analyses, aiding in the understanding of economically significant animal traits.
research Sequence, expression, and evolutionary conservation of a gene encoding a glycine/tyrosine-rich keratin-associated protein of hair.
This research observed that sheep and rabbit KAP6 genes, expressed in hair follicle cells, have high sequence similarity and indicate conservation due to evolutionary selection pressures.
research Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link between the Embryonic Subperiderm and Feather Barbs and Barbules
In this study, researchers found that the EDMTFH protein is present in specific layers of the chicken embryo skin and feathers, suggesting its role in feather mechanics and development.
research Characterization of hairless (Hr) and FGF5genes provides insights into the molecular basis of hair loss in cetaceans
This study found that the Hr gene loss and positive selection for the FGF5 gene in cetaceans likely contributed to hair loss as these animals adapted to aquatic environments.
research Module-based complexity formation: periodic patterning in feathers and hairs
This article reviews the generation of complex integument patterns through genetic, chemical, and environmental influences, with applications in tissue engineering, but reports no new experimental results.
research The nude gene and the skin
This review discusses the molecular and functional aspects of the nude gene in skin biology, providing insights into its role and evolutionary development, but reports no new results.
research The Enigma of the Stigma of Hair Loss: Why is Cancer-Treatment Related Alopecia so Traumatic for Women?
This observational study provides cause-specific mortality estimates to help patients and physicians better understand long-term outcomes for localized prostate cancer based on initial treatment choices.
research Hair, Human Evolution, and the Idea of Human Uniqueness
Human hair is unique and important for understanding human evolution and identity.
research Developmental Plasticity of Patterned and Regenerating Oral Organs
This review discusses the developmental plasticity between teeth and taste buds in cichlid fishes and reports no new experimental findings, highlighting potential implications for craniofacial organ patterning and regeneration.