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This Phase 1 study reported that topical application of BPM31543 was safe and well-tolerated in patients receiving taxane-based chemotherapy, with some experiencing less than 50% hair loss, suggesting potential efficacy in reducing chemotherapy-induced alopecia, although no maximum tolerated dose was identified.

Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.

In this survey of dermatologists, pimozide was most commonly identified as the preferred first-line antipsychotic for treating delusions of parasitosis, followed by risperidone.

This study reported that a novel vasodilator drug called TOP-M119, when delivered using a specially designed dissolving microneedle system, showed enhanced targeting of hair follicles and effectiveness in treating alopecia, demonstrated through in vitro, ex vivo, and in vivo studies involving mouse skin.

Propranolol affects heart rate and renin levels in minoxidil-treated patients.

This editorial discusses the implications of neuroimaging for the treatment of epilepsy and reports no new clinical results; the author emphasizes its potential impact on therapeutic strategies.

This study found that formalin-induced pain in rats nearly eliminates testosterone in the brain and spinal cord by likely increasing 5α-reductase activity, but normalizes serum levels after 24 hours.

Finasteride blocks progesterone's effect on absence seizures in rats.

The article discusses a complication that occurred during a follicular unit extraction hair restoration procedure, presenting an opportunity for the author to learn from the experience and reports no new research findings.

In this study, researchers found that adding zygomaticotemporal nerve blocks to supratrochlear and supraorbital nerve blocks in mesotherapy lowered pain significantly during and after the procedure for hair regrowth in alopecia patients.

This study concluded that 16β-methyl-17α-benzoyloxypregnen-4-en-3,20-dione may be a promising treatment for androgen-dependent diseases and epilepsy due to its antioxidant effects and impact on GABAergic and serotonergic metabolism in rats.

This study developed and tested a finasteride suspension that retains over 94.3% of its initial concentration for up to 90 days at room temperature, finding no airborne finasteride exposure during formulation handling.

This study reports an easy colorimetric method for detecting nitrite in water using minoxidil, which may be suitable for various analytical applications due to its effective detection range.

This study found that compounded minoxidil solutions in a propylene glycol-free and alcohol-reduced foam remained stable for 180 days, meeting United States Pharmacopeia standards for strength, pH, and antimicrobial effectiveness.

Minoxidil in breast milk may harm nursing infants.

This study found that microencapsulation combined with iontophoresis can significantly enhance the delivery of minoxidil sulphate to hair follicles, suggesting a synergetic approach for topical drug targeting.

This study reports a successful combination treatment for phospho-organic compound poisoning, using standard therapy with atropine and toxogonin along with exogenous cholinesterases via blood transfusion, showing positive outcomes in patients whose endogenous cholinesterase levels dropped to 20%.

In this study, high-dose dutasteride significantly reduced several core symptoms of PMDD compared to placebo, supporting the role of neurosteroids in this condition.

This case report describes a rare presentation of myxedema coma in a 46-year-old woman, initially identified by acute pulmonary embolism, which was managed successfully with thyroid hormone and corticosteroid treatment.

In this study, a 68-year-old man with muscle-invasive bladder cancer and renal insufficiency achieved a partial radiological response to neoadjuvant therapy with gemcitabine and Disitamab Vedotin, without significant adverse events, highlighting a potential alternative for cisplatin-ineligible patients.

In this study, the safety profile of the prodrug CAP7.1 was found to be similar to other topoisomerase inhibitors, with myelosuppression as the main dose-limiting toxicity.

This case report suggests that discontinuing finasteride, which may affect neurosteroids synthesis, improved seizure control in a woman with temporal lobe seizures.

This study found that treatment with oral contraceptives containing 35mg ethinylestradiol and 2mg cyproterone acetate significantly reduced serum AMH levels in women with clomiphene citrate-resistant polycystic ovary syndrome, unlike metformin.

This study proposed a simple, rapid permanganometric method for determining minoxidil concentrations in pharmaceutical samples, offering comparable accuracy to chromatographic methods with recovery rates of 94.5 to 95.2%.

This study suggests that 5alpha-dihydroprogesterone could be an effective, non-sedative anticonvulsant for drug-resistant complex partial seizures, as observed in a rat model.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

This study observed that ethylenthiourea's lethality increases with dose accumulation and ethanol co-administration, while impaired liver function and various adverse effects were noted in long-term treated rats.

This case study reported that an 18-year-old woman ingested a large amount of topical minoxidil, leading to symptoms like low blood pressure, increased heart rate, and elevated liver enzymes, but recovered fully after treatment. Minoxidil toxicity may rarely cause abnormal liver enzyme levels.

This study found that pre-treatment with the neurosteroid allopregnanolone in mice reduced nicotine withdrawal symptoms, suggesting potential therapeutic benefits for nicotine dependence.

This study developed a novel mouse model of catamenial epilepsy by manipulating neurosteroid levels and demonstrated that withdrawal increases seizure susceptibility, potentially linked to changes in GABAA receptor-subunit plasticity.