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    Glossary Estrogen Receptor-Positive Breast Cancer

    cancer type where cells grow due to estrogen binding

    Estrogen Receptor-Positive Breast Cancer (ER+ Breast Cancer) is a type of breast cancer where the cancer cells have receptors that bind to the hormone estrogen. This binding promotes the growth of the cancer cells. Treatments often involve hormone therapies that block estrogen from attaching to these receptors, thereby slowing or stopping the cancer's growth.

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    Research 30 of 1000+

    1. The Safety of Local Hormonal Treatment for Vulvovaginal Atrophy in Women With Estrogen Receptor-positive Breast Cancer Who Are on Adjuvant Aromatase Inhibitor Therapy: Meta-analysis Clinical breast cancer · 2019 · 18 citations
    2. Patient-Reported Outcomes From Phase III Neoadjuvant Systemic Trial Comparing Neoadjuvant Chemotherapy With Neoadjuvant Endocrine Therapy in Pre-Menopausal Patients With Estrogen Receptor-Positive and HER2-Negative, Lymph Node-Positive Breast Cancer Frontiers in Oncology · 2021 · 1 citations
    3. A phase 1b study of chemo-immunotherapy with pegylated liposomal doxorubicin and Pembrolizumab in estrogen receptor positive metastatic breast cancer Cancer Research Communications · 2026
    4. Data from A Phase Ib Study of Chemoimmunotherapy with Pegylated Liposomal Doxorubicin and Pembrolizumab in Estrogen Receptor–Positive Metastatic Breast Cancer 2026
    5. Hair regrowth in endocrine therapy alopecia with dutasteride treatment in woman with estrogen positive breast cancer JAAD case reports · 2023
    6. Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells International Journal of Molecular Sciences · 2022 · 8 citations
    7. Estrogen deprivation effects of endocrine therapy in breast cancer patients: Incidence, management and outcome Cancer Treatment Reviews · 2023 · 7 citations
    8. Clinical aspect, pathogenesis and therapy options of alopecia induced by hormonal therapy for breast cancer Exploration of targeted anti-tumor therapy · 2021 · 2 citations
    9. Aldosterone- and cortisol-cosecreting adrenal adenoma, ovarian hyperthecosis and breast cancer Endocrinology, Diabetes & Metabolism Case Reports · 2020 · 1 citations
    10. 202 Activation of breast cancer cell proliferation by ROR-alpha through aromatase promoter Ejc Supplements · 2010
    11. Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents Annals of Oncology · 2005 · 67 citations
    12. Ductal breast cancer in a male patient International Journal of Dermatology · 2010
    13. Cancer risk in polycystic ovary syndrome patients: Common treatments and future perspectives Journal of multidisciplinary sciences (Online) · 2023
    14. Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition Endocrine Reviews · 2005 · 451 citations
    15. Drug safety evaluation of exemestane Expert Opinion on Drug Safety · 2011 · 7 citations
    16. Effect of palbociclib plus letrozole on patient-reported health-related quality of life: extended follow-up of the PALOMA-2 trial ESMO Open · 2025 · 2 citations
    17. Androgen receptor: A promising therapeutic target in breast cancer Critical Reviews in Clinical Laboratory Sciences · 2019 · 21 citations
    18. Aromatase inhibitors induce ‘male pattern hair loss’ in women? Annals of Oncology · 2013 · 19 citations
    19. Estrogens and aging skin Dermato-endocrinology · 2013 · 150 citations
    20. Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm Asia-Pacific Journal of Clinical Oncology · 2018 · 4 citations
    21. Abstract P5-09-21: Selective androgen receptor modulators (SARMs): Enobosarm as targeted therapy for the treatment of androgen receptor-positive breast cancer Cancer research · 2013 · 2 citations
    22. Safety and quality of life of CDK4/6 inhibitors therapy for hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: a multicenter cross-sectional survey in China BMC Cancer · 2025 · 1 citations
    23. NDA Submission of Vepdegestrant (ARV-471) to U.S. FDA: The Beginning of a New Era of PROTAC Degraders Journal of Medicinal Chemistry · 2025 · 45 citations
    24. The evolution of primary multimodality treatment in resectable breast cancer Cancer · 1980 · 13 citations
    25. Female pattern hair loss possibly caused by tamoxifen: Androgen receptor expression in the outer root sheath in the affected area Journal of Dermatology · 2012 · 5 citations
    26. Canadian Expert Recommendations on Safety Overview and Toxicity Management Strategies for Sacituzumab Govitecan Based on Use in Metastatic Triple-Negative Breast Cancer Current Oncology · 2024 · 6 citations
    27. 200 The relationship between the expression of cytokeratin 5/6 and clinicopathologic factors in invasive breast carcinoma Ejc Supplements · 2010
    28. Nutraceuticals Known To Promote Hair Growth Do Not Interfere With The Inhibitory Action of Tamoxifen In MCF7, T47D And BT483 Breast Cancer Cell Lines Research Square (Research Square) · 2022
    29. A systematic review of health-related quality of life outcomes in patients with advanced breast cancer treated with palbociclib Journal of Comparative Effectiveness Research · 2024 · 7 citations
    30. Selective Androgen Receptor Modulators (SARMs) Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial:Mesenchymal Stem Cell Signaling PloS one · 2014 · 56 citations