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Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Birth control pills can help reduce mild to moderate acne in women.

A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.

COVID-19 may worsen with androgens; anti-androgen drugs could help.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

Ficus carica extract improved fertility in rats and may help with certain health conditions.

Herbal hair gel with fenugreek seed extract was found to increase hair growth.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Hair loss, known as Androgenetic Alopecia, is often caused by hormones and can be diagnosed using noninvasive techniques. Treatments include topical minoxidil and oral finasteride, with new treatments being explored. There may also be a link between this type of hair loss and heart disease risk.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

Thyroid function affects skin health, with a complex interaction between the two.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.