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    Glossary Estrogen Deficiency

    insufficient estrogen production affecting reproductive health and bone density

    Estrogen deficiency, also known as low estrogen, occurs when the body produces insufficient levels of estrogen, a key hormone in regulating the reproductive system and secondary sexual characteristics. This condition can lead to symptoms such as irregular menstrual cycles, hot flashes, mood swings, and can increase the risk of osteoporosis due to decreased bone density. It is commonly seen in postmenopausal women but can also affect younger women due to various medical conditions or treatments.

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    1. Anatomical and Dermatologic Manifestations of Estrogen Deficiency in Postmenopausal Women: A Systematic Review Pakistan Journal of Health Sciences · 2025
    2. MANAGING ESTROGEN-DEFICIENT SKIN: A NARRATIVE REVIEW ON THE ROLE OF HRT AND EMERGING ESTROGEN-MODULATING THERAPIES International Journal of Innovative Technologies in Social Science · 2025
    3. SAT-130 Estrogen deficiency in patients with reduced fat mass as a cause of non-alcoholic fatty liver disease Journal of the Endocrine Society · 2025
    4. PSAT217 Estrogen Deficiency as a Cause of Decreased 1- alpha - hydroxylase Activity Journal of the Endocrine Society · 2022
    5. The role of estrogen in cutaneous ageing and repair Maturitas · 2017 · 158 citations
    6. Estrogens and aging skin Dermato-endocrinology · 2013 · 150 citations
    7. Impact of estrogens in males and androgens in females 2019 · 120 citations
    8. Aromatase deficiency in a male patient - Case report and review of the literature. Bone · 2016 · 36 citations
    9. Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells International Journal of Molecular Sciences · 2022 · 8 citations
    10. Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels -A Narrative Review. PubMed · 2026
    11. Cutaneous manifestations of endocrine-metabolic disease and nutritional deficiency in the elderly Dermatologic Clinics · 2004 · 18 citations
    12. Disorders of sex development (DSD) 46.XY due to type 2 5-α reductase deficiency in three siblings: Case report from a low-resource setting Annals of medicine and surgery · 2022
    13. [Epididymis in an experimental model of DHT deficiency: immunolocalization of ERalpha and ERbeta in rat epididymal epithelial cells. In vivo and in vitro studies]. PubMed · 2006 · 4 citations
    14. Determinants of Plasma Androgen and Estrogen Levels in Men Data Archiving and Networked Services (DANS) · 2006
    15. Skin connective tissue and ageing Best Practice & Research in Clinical Obstetrics & Gynaecology · 2013 · 77 citations
    16. Skin ageing Menopause International · 2007 · 76 citations
    17. Menopause and aging, quality of life and sexuality Climacteric · 2007 · 55 citations
    18. Young coconut juice can accelerate the healing process of cutaneous wounds BMC Complementary and Alternative Medicine · 2012 · 19 citations
    19. [Hormone replacement treatment and skin aging]. PubMed · 1996 · 16 citations
    20. Testosterone Treatment in Women – An Overview Current Women's Health Reviews · 2009 · 8 citations
    21. Metabolic Syndrome, Hepatic Steatosis and Testosterone: A Matter of Sex Livers · 2024 · 7 citations
    22. Human skin Menopause · 2016 · 6 citations
    23. Dermatological effects of menopausal hormone therapy: A path to overcoming hormone phobia Meditsinskiy sovet = Medical Council · 2026
    24. The Hormonal Background of Hair Loss in Non-Scarring Alopecias Biomedicines · 2024
    25. Mechanisms of testosterone action 2021
    26. News-Screen Menopause: Haarausfall in der Menopause Journal für Kardiologie (Krause & Pachernegg GmbH) · 2011
    27. Causes of hair loss and the developments in hair rejuvenation International Journal of Cosmetic Science · 2002 · 69 citations
    28. The therapeutic use of androgens in women The Journal of Steroid Biochemistry and Molecular Biology · 1999 · 51 citations
    29. Changes of androgens levels in menopausal women Przegląd Menopauzalny · 2020 · 26 citations
    30. Hormonale Diagnostik der sogenannten androgenetischen Alopezie der Frau Geburtshilfe und Frauenheilkunde · 1988 · 25 citations