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    GlossaryEstrogen Deficiency

    insufficient estrogen production affecting reproductive health and bone density

    Estrogen deficiency, also known as low estrogen, occurs when the body produces insufficient levels of estrogen, a key hormone in regulating the reproductive system and secondary sexual characteristics. This condition can lead to symptoms such as irregular menstrual cycles, hot flashes, mood swings, and can increase the risk of osteoporosis due to decreased bone density. It is commonly seen in postmenopausal women but can also affect younger women due to various medical conditions or treatments.

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      Human Skin

      research Human Skin

      6 citations, January 2016 in “Menopause”
      Estrogen deficiency, like after menopause or certain surgeries, leads to faster skin aging and health issues.
      Protective Cardiovascular and Renal Actions of Vitamin D and Estrogen

      research Protective Cardiovascular and Renal Actions of Vitamin D and Estrogen

      13 citations, December 2012 in “Frontiers in bioscience”
      Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
      Estrogens and Aging Skin

      research Estrogens and Aging Skin

      150 citations, April 2013 in “Dermato-endocrinology”
      Estrogen therapy can reduce skin aging but has cancer risks.
      Skin Connective Tissue and Aging

      research Skin Connective Tissue and Aging

      77 citations, July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”
      Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
      Skin Aging

      research Skin Aging

      76 citations, May 2007 in “Menopause International”
      After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.
      Testosterone Treatment in Women: An Overview

      research Testosterone Treatment in Women: An Overview

      8 citations, February 2009 in “Current Women's Health Reviews”
      Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

      research Mechanisms of Testosterone Action

      January 2021
      Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
      Menstrual Irregularity in Women with Acromegaly

      research Menstrual Irregularity in Women with Acromegaly

      66 citations, August 1999 in “The Journal of Clinical Endocrinology & Metabolism”
      Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.
      Gonadal Dysgenesis and Bone Metabolism

      research Gonadal Dysgenesis and Bone Metabolism

      45 citations, February 2001 in “Joint bone spine”
      Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
      The Effects of Estrogens on Linear Bone Growth

      research The Effects of Estrogens on Linear Bone Growth

      11 citations, July 2001 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS”
      Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.
      Estrogens and the Skin

      research Estrogens and the Skin

      137 citations, June 2005 in “Climacteric”
      Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
      Oligomenorrhea in Exercising Women

      research Oligomenorrhea in Exercising Women

      11 citations, November 2009 in “Sports Medicine”
      Irregular menstrual cycles in exercising women may be linked to energy deficiency or hormonal imbalances, requiring careful diagnosis for proper treatment.
      Summary of the Recommendations on Sexual Dysfunctions in Women

      research Summary of the Recommendations on Sexual Dysfunctions in Women

      177 citations, July 2004 in “The Journal of Sexual Medicine”
      Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.
      Hormone Replacement Therapy and the Skin

      research Hormone Replacement Therapy and the Skin

      138 citations, May 2000 in “Maturitas”
      Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
      Treatment of Hyperandrogenism in Women

      research Treatment of Hyperandrogenism in Women

      8 citations, January 1996 in “Gynecological Endocrinology”
      Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
      Promoting Longevity: A Global Approach

      research Promoting Longevity: A Global Approach

      1 citations, May 2017 in “Maturitas”
      The document concludes that managing health issues like menopause, cardiovascular risk, and hair loss is crucial for promoting longevity in aging women.
      Skin Aging and Menopause: Implications for Treatment

      research Skin Aging and Menopause: Implications for Treatment

      180 citations, January 2003 in “American Journal of Clinical Dermatology”
      Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
      Endocrinology of Transgender Medicine

      research Endocrinology of Transgender Medicine

      166 citations, October 2018 in “Endocrine Reviews”
      Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

      research Hormonal Effects on Hair Follicles

      102 citations, July 2020 in “International journal of molecular sciences”
      Hormones like testosterone and estrogen significantly affect hair growth and structure.
      Current Evaluation of Amenorrhea

      research Current Evaluation of Amenorrhea

      78 citations, November 2008 in “Fertility and Sterility”
      Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.