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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Use minoxidil for hair loss treatment; assess results after 6 months.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Finasteride may cause long-lasting sexual side effects.