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research THE IMPORTANCE OF TRANS-ESOPHAGEAL ECHOCARDIOGRAPHY IN DIAGNOSING LIBMAN-SACKS ENDOCARDITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS: A CASE REPORT
This case report highlights the importance of trans-esophageal echocardiography in distinguishing Libman-Sacks endocarditis from infective endocarditis in systemic lupus erythematosus patients, guiding appropriate treatment for associated cerebrovascular disease.
research Exosomes in Cosmetic Dermatology: A Review of Benefits and Challenges
In this literature review, exosomes show promise in cosmetic dermatology for skin rejuvenation and hair restoration; however, challenges like inconsistent isolation methods and lack of FDA approval necessitate further clinical trials to ensure long-term safety and efficacy.
research Aesthetic Importance of the Parietal Eminence Area (Posterior Parietal Triangle), an Essential Island of Scalp Requiring Hair Restoration
This study concluded that hair transplants including the parietal eminence area can enhance aesthetic balance and provide indirect cosmetic benefits, even when the vertex is left untreated due to limited donor availability.
research Scarring, stem cells, scaffolds and skin repair
This review examines the role of endothelial precursors and cellularized scaffolds in wound repair and revascularization for treating full thickness skin loss, but reports no new clinical results.
research 1418 Characterization of ectomesenchyme as an origin of epidermal stem cells
This study identified ectomesenchyme as a major source of epidermal stem cells in mouse skin, with ectomesenchymal keratinocytes occupying a significant portion of the epidermal stem cell-enriched population.
research Cultured Keratinocyte Sheets Enhanced Spontaneous Re-Epithelialization in a Dermal Explant Model of Partial-Thickness Wound Healing
research Reepithelialization of a Full-Thickness Burn from Stem Cells of Hair Follicles Micrografted into a Tissue-Engineered Dermal Template (Integra)
In this study, researchers achieved complete reepithelialization and hair growth on a burn-injured scalp using a tissue-engineered dermal template with early micrograft hair follicle implantation.
research Platelet-rich gel versus external tissue expansion technique in treating scalp defects: A retrospective study
This study observed that platelet-rich gel for scalp defect reconstruction was more cost-effective and less painful but resulted in poorer hair growth compared to the external tissue expansion technique.
research Stem-cell clinics in the UK: a web-based study
This study found that the majority of UK clinics market stem cell treatments ethically questionably, often omitting risk information, exaggerating effectiveness, and using celebrity testimonials.
research Adipose-derived stem cell exosomes promote critical-sized bone defect repair by enhancing the homing of bone marrow mesenchymal stem cells
This study observed that exosomes derived from adipose-derived stem cells significantly enhanced bone marrow mesenchymal stem cell migration and osteogenesis, leading to improved bone regeneration in a rat model of calvarial defects.
research The role of estrogen in cutaneous ageing and repair
This review discusses the role of estrogen deficiency in post-menopausal skin aging and wound healing, highlighting opportunities for developing estrogen receptor-targeted therapies and reports no new clinical results.
research The Anti-Aging Effects of Adipose-Derived Mesenchymal Stem Cell Exosomes on Skin and Their Potential for Personalized Skincare Applications
This narrative review highlights the potential of autologous adipose mesenchymal stem cell-derived exosomes (AMSCs-Exos) in anti-skin aging, noting their superior biocompatibility and manufacturing advantages while stressing the need for standardized production protocols to overcome existing application challenges.
research Marketing Experimental Stem Cell Therapies in the UK: Biomedical Lifestyle Products and the Promise of Regenerative Medicine in the Digital Era
This study discusses the rise of commercial direct-to-consumer stem cell therapies, highlighting how they are marketed as biomedical 'lifestyle' products that blend science, medicine, and consumer culture, despite ongoing safety and efficacy concerns.
research Guided Superficial Enhanced Fluid Fat Injection (SEFFI) Procedures for Facial Rejuvenation: An Italian Multicenter Retrospective Case Reports
This study found that the guided SEFFI technique for facial volume restoration and anti-aging is minimally invasive with a low complication rate, suggesting it as a promising treatment option.
research Beau's Lines
This case report describes a 75-year-old woman with pustular psoriasis who developed Beau's lines on her nails, coinciding with episodes of telogen effluvium.
research STITCH: Augmented Dexterity for Suture Throws Including Thread Coordination and Handoffs
In this study, the researchers developed an advanced robotic system called STITCH for performing suture tasks, which completed an average of 2.93 sutures autonomously and 4.47 sutures with human intervention in physical trials.
research Shaping epithelial tissues by stem cell mechanics in development and cancer
research Exosomes in Facial Plastic Surgery
In this research, preclinical and early clinical studies on exosomes indicate their potential to modulate wound healing, skin rejuvenation, and hair growth in facial plastic surgery, but these treatments remain experimental until receiving FDA approval and robust clinical validation.
research "A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems''
This paper discusses ethosomal drug delivery systems, highlighting their improved ability to enhance skin penetration and increase therapeutic effectiveness in treatments like acyclovir for herpes labialis and minoxidil for androgenic alopecia compared to standard formulations.
research Mechano-encoding hydrogel microspheres for extracellular and pericellular matrix remodeling in musculoskeletal organoids
This review focuses on hydrogel microsphere-mediated strategies to improve organoid culture by addressing deficiencies in extracellular matrix organization, potentially enhancing the physiological accuracy and clinical translatability of osteomuscular in vitro models as reported in this study.
research Essential Fatty Acid Deficiency (EFAD) in a Patient with Vascular Ehlers Danlos Syndrome (EDS-4) (P12-053-19)
This case study reports that pancreatic enzyme replacement and fatty acid supplementation improved symptoms of fat malabsorption and essential fatty acid deficiency in a patient with EDS-4.
research Achieving Physiologic 17-ẞ-Estradiol Levels in Transgender Females on Estradiol Transdermal Patches and Optimal Dosing
This study found that estradiol transdermal patches helped many MTF patients achieve target estrogen levels, especially those who could not reach these levels with oral therapy and those at higher thrombotic risk.
research Exosomes in Hair Restoration
research P-18 THREE BODY PROBLEM PATIENT: EHLER DANLOS SYNDROME COMBINED WITH HYPOPHOSPHATASIA AND FATTY ACID OXIDATION DEFECT
This report describes a 27-year-old patient with Ehler-Danlos syndrome who also presented with hypophosphatasia and mastocytosis, and suggests enzyme replacement therapy might alleviate symptoms in such overlapping genetic conditions.
research Looking Beyond PRP, Exosomes, and Stem Cells
This review highlights the significant advancements in regenerative medicine from stem cells, PRP, and exosomes for dermatology, but notes that regulatory challenges and the need for standardization are slowing their clinical application.
research Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
This study reviews the roles and mechanisms of MSC-derived exosomes in wound healing, noting their potential as promising cell-free therapies for cutaneous regeneration.
research Therapeutic potential of Asiaticoside in wound healing after endoscopic submucosal dissection (ESD)
This review discusses the potential of asiaticoside from Centella asiatica for enhancing wound healing after endoscopic submucosal dissection and highlights delivery strategies to improve its gastrointestinal application; it reports no new clinical results.
research 577 Successful allogeneic epidermal grafting of chronic recessive dystrophic epidermolysis bullosa wounds from hematopoietic cell donors in the outpatient setting
This study found that post-hematopoietic cell transplantation epidermal grafting significantly reduced chronic wound size in patients with recessive dystrophic epidermolysis bullosa.
research Exosome as a Therapeutic Agent in Cosmetic Dermatology
This chapter highlights the potential of exosomes as innovative agents in cosmetic dermatology, noting their ability to promote skin rejuvenation and target issues like wrinkles, photoaging, and hair loss.