research Bioactive Compounds from the Roots of Asiasarum Heterotropoides
Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.
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research Acute Sensitivity of the Oral Mucosa to Oncogenic K-ras
Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.
research Anaemia and Skin Disease
Some skin diseases and anaemia are related, and treating the skin condition can often improve the anaemia.
research Distinct Conditions Support a Novel Classification for Bradykinin-Mediated Angioedema
The conclusion suggests a new way to classify bradykinin-mediated angio-oedema based on different causes and its possible link with urticaria, which could improve diagnosis and treatment.
research Comparative Evaluation Between Two Nutritional Supplements in the Improvement of Telogen Effluvium
One supplement improved hair loss and quality faster and more effectively than the other in treating telogen effluvium.
research A Machine Learning and Network Framework to Discover New Indications for Small Molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Preponderance of Serum and Intra-Hepatic 5α-Dihydrotestosterone in Males with Hepatocellular Carcinoma Despite Low Circulating Androgen Levels
Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.
research Possible Intermediary Role of Ghrelin in Seborrhea
The conclusion suggests that the hormone ghrelin might link acid reflux to oily skin.
research Management of Hidradenitis Suppurativa
Effective treatment for hidradenitis suppurativa varies, with antibiotics commonly used and surgery as an option, but no single method is universally successful.
research Clinical Guidance on the Monitoring and Management of Trastuzumab Deruxtecan (T-DXd)-Related Adverse Events: Insights from an Asia-Pacific Multidisciplinary Panel
Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.
research Non-FDA-Approved Uses of Apremilast in Dermatology: A Review of Current Available Literature
Apremilast shows promise for several skin conditions but needs more research.
research Book Reviews
The document concludes that each reviewed medical book is useful for its specific area in pediatric care, especially the "Neonatal Formulary" for neonatal drug information.
research Dermatological Adverse Effects of Chemotherapeutic Agents: Experience from a Tertiary Centre
About 22% of cancer patients had skin-related side effects from chemotherapy, but these were usually not severe enough to halt treatment.
research Connective Tissue Disorders
Different connective tissue disorders have unique symptoms and treatments, with varying outcomes and often require ongoing care from a specialist.
research British Society for Dermatopathology: Summaries of Papers
Some skin conditions are associated with other serious diseases, and office microscopy may miss many fungal infections.
research Induction of Cellular Senescence and Hair Follicle Stem Cell Dysfunction Upon p14ARF and p16Ink4a Expression in the Skin
p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.
research Functional Enhancers as Master Regulators of Tissue-Specific Gene Regulation and Cancer Development
Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.
research MicroRNA-21 in Skin Fibrosis: Potential for Diagnosis and Treatment
MicroRNA-21 could help diagnose and treat skin fibrosis.
research Sequence and Expression of Human Hair Keratin Genes
Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.
research Flavonoids and Saponins: What Have We Got or Missed?
More high-quality research is needed to recommend flavonoids and saponins for clinical use.
research Hyperandrogenism and Menstrual Imbalance Are the Best Predictors of Metformin Response in PCOS Patients
High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.
research Interstitial Pneumonia with Autoimmune Features: Challenges and Controversies
The document concludes that diagnosing and treating Interstitial Pneumonia with Autoimmune Features (IPAF) is challenging, needs a multidisciplinary approach, and further research for better diagnostic criteria and treatments. It also emphasizes regular checks for Connective Tissue Disease symptoms in all patients with Interstitial Lung Disease.
research Bariatric Surgery for Spontaneous Ovulation in Women with Polycystic Ovary Syndrome: The BAMBINI Multicentre, Open-Label, Randomised Controlled Trial
Bariatric surgery improves ovulation rates in women with PCOS and obesity better than medical therapy.
research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases
Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
research Outcomes of Pediatric Patients with Chronic Liver Disease in Early Adulthood: A Heterogeneous but Representative Regional Cohort Study
Young adults who had liver disease as children often experience significant health problems and frequently need transplants.
research A Systematic Review on Drug Re-Profiling/Re-Purposing
The document concludes that drug repurposing, which is reusing known medicines for new illnesses, can provide faster, cheaper treatment options for various serious diseases, including cancer, COVID-19, and rare diseases.
research Schmallenberg Virus Infection Suspected in a Calf Born to an Imported Heifer
A calf in Scotland likely had Schmallenberg virus from its mother.