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Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Improving the environment and cell interactions is key for creating human hair in the lab.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Injected human hair follicle cells can create new, small hair follicles in skin cultures.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

The document concludes that surgery is a preferred treatment for cicatricial alopecia, with the method chosen based on individual factors and may require multiple sessions and careful postoperative care.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.