4 citations,
March 2014 in “The FASEB Journal” The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.
April 2018 in “Journal of Investigative Dermatology” A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.
64 citations,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
64 citations,
August 2007 in “Artificial Organs” PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.
55 citations,
April 2017 in “Experimental Dermatology” The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.
19 citations,
September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
7 citations,
January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
3 citations,
June 2017 in “International Journal of Radiation Biology” Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.
20 citations,
July 2008 in “Dermatologic Therapy” The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
18 citations,
October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
49 citations,
December 2009 in “Journal of Investigative Dermatology” Thyroid function affects skin health, with a complex interaction between the two.
12 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.
16 citations,
May 2000 in “Endocrinology” A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.
August 2023 in “Micromachines” The new method can create hair follicle-like structures but not complete hair with roots and shafts, needing more improvement.
26 citations,
January 2007 in “Organogenesis” Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
20 citations,
October 2017 in “Stem Cell Reports” Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.
450 citations,
January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
49 citations,
September 2007 in “Journal of Investigative Dermatology” The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
32 citations,
April 2017 in “Scientific Reports” Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
25 citations,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
January 2000 in “BioScience” The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.
211 citations,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
165 citations,
December 2004 in “Differentiation” BMP signaling is crucial for skin and hair growth.
67 citations,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
41 citations,
September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
15 citations,
March 2022 in “Acta Biomaterialia” The new 3D bioprinting method successfully regenerated hair follicles and shows promise for treating hair loss.
10 citations,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
8 citations,
October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
7 citations,
September 2022 in “International journal of molecular sciences” The research found that the molecule lncRNA-H19 helps hair follicle cells grow by affecting certain cell pathways in cashmere goats.
4 citations,
July 2022 in “Annals of translational medicine” Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.